Evidence map›Paper›PMID 40710621›Full record

ArticleJournal of imaging2025

MST-AI: Skin Color Estimation in Skin Cancer Datasets.

Vahid Khalkhali, Hayan Lee, Joseph Nguyen, Sergio Zamora-Erazo, Camille Ragin, Abhishek Aphale, Alfonso Bellacosa, Ellis P Monk, Saroj K Biswas

Abstract read
In one paragraph

Article in Journal of imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vahid KhalkhaliElectrical and Computer Engineering Department, Temple University, Philadelphia, PA 19122, USA.
Hayan LeeCancer Epigenetics Institute, Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.ORCID 0000-0003-0571-3192
Joseph NguyenCancer Epigenetics Institute, Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.ORCID 0009-0006-4572-3159
Sergio Zamora-ErazoCancer Epigenetics Institute, Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.ORCID 0009-0001-1057-736X
Camille RaginCancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.ORCID 0000-0003-0816-4942
Abhishek AphaleDivision of Dermatology, Melanoma and Skin Cancer Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Alfonso BellacosaCancer Epigenetics Institute, Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Ellis P MonkDepartment of Sociology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-3124-0990
Saroj K BiswasElectrical and Computer Engineering Department, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0002-5464-1773

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Eric Andrew Ross · 1985 to 2026
$138.8M
Fox Chase Cancer Center StartupNCI NIH HHS P30 CA006927
6 · The paper itself

Abstract

The absence of skin color information in skin cancer datasets poses a significant challenge for accurate diagnosis using artificial intelligence models, particularly for non-white populations. In this paper, based on the Monk Skin Tone (MST) scale, which is less biased than the Fitzpatrick scale, we propose MST-AI, a novel method for detecting skin color in images of large datasets, such as the International Skin Imaging Collaboration (ISIC) archive. The approach includes automatic frame, lesion removal, and lesion segmentation using convolutional neural networks, and modeling normal skin tones with a Variational Bayesian Gaussian Mixture Model (VB-GMM). The distribution of skin color predictions was compared with MST scale probability distribution functions (PDFs) using the Kullback-Leibler Divergence (KLD) metric. Validation against manual annotations and comparison with K-means clustering of image and skin mean RGBs demonstrated the superior performance of the MST-AI, with Kendall's Tau, Spearman's Rho, and Normalized Discounted Cumulative Gain (NDGC) of 0.68, 0.69, and 1.00, respectively. This research lays the groundwork for developing unbiased AI models for early skin cancer diagnosis by addressing skin color imbalances in large datasets.

Indexed as

artificial intelligence (AI)bias reductionMonk Skin Tone (MST) scaleskin cancer detectionskin color detection

Identifiers

PMID40710621
PMCPMC12295582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.