Evidence map›Paper›PMID 40710589›Full record

ArticleMetabolites2025

Decoding Fish Origins: How Metals and Metabolites Differentiate Wild, Cultured, and Escaped Specimens.

Warda Badaoui, Kilian Toledo-Guedes, Juan Manuel Valero-Rodriguez, Adrian Villar-Montalt, Frutos C Marhuenda-Egea

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Warda BadaouiDepartment of Biochemistry and Molecular Biology and Agricultural Chemistry and Edafology, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.
Kilian Toledo-GuedesDepartment of Marine Sciences and Applied Biology, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.ORCID 0000-0002-6819-1902
Juan Manuel Valero-RodriguezDepartment of Biological Sciences, University of Bergen, P.O. Box 7803, 5020 Bergen, Norway.ORCID 0000-0002-1603-7516
Adrian Villar-MontaltDepartment of Marine Sciences and Applied Biology, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.
Frutos C Marhuenda-EgeaDepartment of Biochemistry and Molecular Biology and Agricultural Chemistry and Edafology, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 Alicante, Spain.ORCID 0000-0002-0402-9770

Funding

Biodiversity Foundation of the Spanish Ministry for the Ecological Transition and Demographic Challenge THINKINAZUL/2021/044-TOWARDS
6 · The paper itself

Abstract

backgroundFish escape events from aquaculture facilities are increasing and pose significant ecological, economic, and traceability concerns. Accurate methods to differentiate between wild, cultured, and escaped fish are essential for fishery management and seafood authentication.

methodsThis study analyzed muscle tissue from

resultsWild seabream showed significantly higher levels of arsenic (9.5-fold), selenium (3.5-fold), and DHA and ARA fatty acids (3.2-fold), while cultured fish exhibited increased linoleic and linolenic acids (6.5-fold). TMAO concentrations were up to 5.3-fold higher in wild fish, serving as a robust metabolic biomarker. Escaped fish displayed intermediate biochemical profiles. Multivariate models achieved a 100% classification accuracy across species and analytical techniques.

conclusionsThe integration of heavy metal analysis, fatty acid profiling, and NMR-based metabolomics enables the accurate differentiation of fish origin. While muscle tissue provides reliable biomarkers relevant to human exposure, future studies should explore additional tissues such as liver and gills to improve the resolution of traceability. These methods support seafood authentication, enhance aquaculture traceability, and aid in managing the ecological impacts of escape events.

Indexed as

aquaculture escapesenvironmental biomarkersfatty acid profilingfish traceabilityheavy metalsmarine fish ecologyNMR metabolomicsseafood authentication

Identifiers

PMID40710589
PMCPMC12300318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.