Evidence map›Paper›PMID 40710566›Full record

ArticleMetabolites2025

Amelioration of Metabolic Syndrome by Co-Administration of

Matias Russo, Antonela Marquez, Estefanía Andrada, Sebastián Torres, Arlette Santacruz, Roxana Medina, Paola Gauffin-Cano

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matias RussoCentro de Referencia para Lactobacilos (CERELA-FML-FECIC-CONICET), San Miguel de Tucumán T4000ILC, Tucumán, Argentina.ORCID 0000-0002-0976-7414
Antonela MarquezCentro de Referencia para Lactobacilos (CERELA-FML-FECIC-CONICET), San Miguel de Tucumán T4000ILC, Tucumán, Argentina.ORCID 0000-0001-9465-618X
Estefanía AndradaCentro de Referencia para Lactobacilos (CERELA-FML-FECIC-CONICET), San Miguel de Tucumán T4000ILC, Tucumán, Argentina.ORCID 0000-0002-4084-6946
Sebastián TorresInstituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), San Miguel de Tucumán T4000ILC, Tucumán, Argentina.
Arlette SantacruzSchool of Engineering and Science, Tecnologico de Monterrey, Av. Eugenio Garza Sada 2501 Sur, Monterrey C.P. 64849, Nuevo León, Mexico.
Roxana MedinaCentro de Referencia para Lactobacilos (CERELA-FML-FECIC-CONICET), San Miguel de Tucumán T4000ILC, Tucumán, Argentina.ORCID 0000-0003-1828-645X
Paola Gauffin-CanoCentro de Referencia para Lactobacilos (CERELA-FML-FECIC-CONICET), San Miguel de Tucumán T4000ILC, Tucumán, Argentina.

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP 0406Consejo Nacional de Investigaciones Científicas y Técnicas PIP 0869FONCyT PICT-2020-03777National University of Tucumán PIUNT A722
6 · The paper itself

Abstract

BACKGROUND/

objectives

methodsMice were divided into three groups and fed for 14 weeks as follows: the Control group (standard diet), the MS group (HFD+WB), and the MS+Lj group (HFD+WB and

resultsImprovements in the MS+Lj group compared to the MS group included the following: a-a 38% increase in colonic FE activity, leading to elevated levels of FA-derived metabolites (e.g., dihydroferulic, dihydroxyphenylpropionic, and hydroxyphenylpropionic acids); b-a significant shift in the IM composition, with a 3.4-fold decrease in Firmicutes and a 2.9-fold increase in Bacteroidetes; c-a decrease in harmful bacteria (

conclusionsThe co-administration of

Indexed as

ferulic acidferuloyl esterasehigh fat dietintestinal microbiotaLactobacillus johnsoniimetabolic syndromeprobiotic

Identifiers

PMID40710566
PMCPMC12299901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.