Evidence map›Paper›PMID 40710561›Full record

ArticleMetabolites2025

ATP Supply from Cytosol to Mitochondria Is an Additional Role of Aerobic Glycolysis to Prevent Programmed Cell Death by Maintenance of Mitochondrial Membrane Potential.

Akane Sawai, Takeo Taniguchi, Kohsuke Noguchi, Taisuke Seike, Nobuyuki Okahashi, Masak Takaine, Fumio Matsuda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akane SawaiDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka, 1-5 Yamadaoka, Suita 565-0871, Japan.
Takeo TaniguchiDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka, 1-5 Yamadaoka, Suita 565-0871, Japan.ORCID 0009-0001-0510-6950
Kohsuke NoguchiDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka, 1-5 Yamadaoka, Suita 565-0871, Japan.
Taisuke SeikeDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka, 1-5 Yamadaoka, Suita 565-0871, Japan.ORCID 0000-0002-8738-7759
Nobuyuki OkahashiDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka, 1-5 Yamadaoka, Suita 565-0871, Japan.ORCID 0000-0001-9582-355X
Masak TakaineGunma University Initiative for Advanced Research (GIAR), Gunma University, 4-2 Aramaki-machi, Maebashi 371-0044, Japan.ORCID 0000-0002-1279-9505
Fumio MatsudaDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka, 1-5 Yamadaoka, Suita 565-0871, Japan.

Funding

Grant-in-Aid for Scientific Research 17H06303Grants in Aid for Scientific Research (B) 22H01879JST CREST JPMJCR21N2
6 · The paper itself

Abstract

Eukaryotic cells generate ATP primarily via oxidative and substrate-level phosphorylation. Despite the superior efficiency of oxidative phosphorylation, eukaryotic cells often use both pathways as aerobic glycolysis, even in the presence of oxygen. However, its role in cell survival remains poorly understood.

Indexed as

aerobic glycolysisbreast cancer cellsmetabolic rewiringmitochondrial membrane potentialprogrammed cell deathreverse mode of H+/ATPaseSaccharomyces cerevisiae

Identifiers

PMID40710561
PMCPMC12299498

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.