ArticleMetabolites2025
Multi-Omics Analysis of Gut Microbiota and Sperm Quality in Tibetan Breeding Boars.
Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Epimedii Folium Supplementation Improves Semen Quality, Hormonal Profile, and Immune Function by Modulating Gut Microbiota and Seminal Metabolites in Aged Boars.Animals : an open access journal from MDPI · 2026Article
- Integrated Metagenomic and Metabolomic Profiling of Boar Semen During Ambient-Temperature Storage.Microorganisms · 2026Article
- Wu Zi Yan Zong Wan enhances sperm quality in boars by regulating spermatogenesis-related pathways and gut microbiota.Frontiers in veterinary science · 2026Article
Corrections and comments
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Authors and funding
7 authors.
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Abstract
BACKGROUND/
objectivesReproductive efficiency in breeding boars critically impacts swine industry productivity, with sperm quality being multifactorially regulated by gut microbiota. This study aimed to elucidate the microbiota-metabolite interactions underlying sperm quality differences in Tibetan boars.
methodsIntegrated 16S rRNA sequencing and untargeted metabolomics were performed on fecal and semen samples from eight healthy Tibetan boars (31-33 months old), stratified into low-semen (CJ) and high-semen utilization (HJ) groups. Analyses included sperm quality assessment, microbial profiling, and metabolic pathway enrichment.
resultsThe HJ group exhibited significantly enhanced sperm motility and semen utilization rates (
conclusionsGut microbiota regulated the sperm microenvironment via a "metabolic-immune" dual pathway mediated by the gut-testis axis. These findings establish a theoretical basis for probiotic or metabolite-targeted strategies to improve boar reproductive performance.
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