Evidence map›Paper›PMID 40710487›Full record

ArticleMarine drugs2025

Didemnosides A and B: Antiproliferative Nucleosides from the Red Sea Marine Tunicate

Lamiaa A Shaala, Diaa T A Youssef, Hadeel Almagthali, Ameen M Almohammadi, Wafaa T Arab, Torki Alzughaibi, Noor M Bataweel, Reham S Ibrahim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lamiaa A ShaalaSuez Canal University Hospitals, Suez Canal University, Ismailia 41522, Egypt.
Diaa T A YoussefDepartment of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-2217-4039
Hadeel AlmagthaliDepartment of Pharmacognosy, College of Pharmacy, Taif University, Al-Haweiah 21974, Saudi Arabia.
Ameen M AlmohammadiDepartment of Pharmacy Practice, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Wafaa T ArabVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-6074-8040
Torki AlzughaibiKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-2855-5134
Noor M BataweelDepartment of Biological Science, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-1845-2374
Reham S IbrahimDepartment of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.

Funding

Institutional Fund Project, Ministry of Education and King Abdulaziz University, DSR, Jeddah, Saudi Arabia IFPIP: 601-166-1443
6 · The paper itself

Abstract

Marine tunicates are a very attractive and abundant source of secondary metabolites with chemical diversity and biological activity. Fractionation and purification of the organic extract of the Red Sea tunicate

Indexed as

Antineoplastic AgentsNucleosidesUrochordataAnimalsAquatic OrganismsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansIndian OceanInhibitory Concentration 50MCF-7 CellsMolecular Docking SimulationPC-3 CellsAntineoplastic AgentsNucleosidesantiproliferative activitybioactive compoundsdidemnosides A and BDidemnum specieshuman cancer cell linesmolecular dockingRed Sea tunicate

Identifiers

PMID40710487
PMCPMC12298903

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.