Evidence map›Paper›PMID 40710481›Full record

ArticleJournal of functional biomaterials2025

The Integration of Micro-CT Imaging and Finite Element Simulations for Modelling Tooth-Inlay Systems for Mechanical Stress Analysis: A Preliminary Study.

Nikoleta Nikolova, Miryana Raykovska, Nikolay Petkov, Martin Tsvetkov, Ivan Georgiev, Eugeni Koytchev, Roumen Iankov, Mariana Dimova-Gabrovska, Angela Gusiyska

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nikoleta NikolovaDepartment of Conservative Dentistry, Faculty of Dental Medicine, Medical University Sofia, 1431 Sofia, Bulgaria.ORCID 0009-0006-6836-9148
Miryana RaykovskaInstitute of Information and Communication Technologies, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-4106-3078
Nikolay PetkovInstitute of Information and Communication Technologies, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0009-0005-1555-9020
Martin TsvetkovInstitute of Mathematics and Informatics, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0009-0001-7929-3816
Ivan GeorgievInstitute of Information and Communication Technologies, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Eugeni KoytchevInstitute of Mechanics, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-9204-6978
Roumen IankovInstitute of Mechanics, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Mariana Dimova-GabrovskaDepartment of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University Sofia, 1431 Sofia, Bulgaria.
Angela GusiyskaDepartment of Conservative Dentistry, Faculty of Dental Medicine, Medical University Sofia, 1431 Sofia, Bulgaria.

Funding

Bulgarian Science Fund and- GRANT D-138/29.05.2024 D-138/29.05.2024
6 · The paper itself

Abstract

This study presents a methodology for developing and validating digital models of tooth-inlay systems, aiming to trace the complete workflow from clinical procedures to simulation by involving dental professionals-dentists for manual cavity preparation and dental technicians for restoration modelling-while integrating micro-computed tomography (micro-CT) imaging with finite element analysis (FEA). The proposed workflow includes (1) the acquisition of high-resolution 3D micro-CT scans of a non-restored tooth, (2) image segmentation and reconstruction to create anatomically accurate digital twins and mesh generation, (3) the selection of proper resin and the 3D printing of four typodonts, (4) the manual preparation of cavities on the typodonts, (5) the acquisition of high-resolution 3D micro-CT scans of the typodonts, (6) mesh generation, digital inlay and onlay modelling and material property assignment, and (7) nonlinear FEA simulations under representative masticatory loading. The approach enables the visualisation of stress and deformation patterns, with preliminary results indicating stress concentrations at the tooth-restoration interface integrating different cavity alternatives and restorations on the same tooth. Quantitative outputs include von Mises stress, strain energy density, and displacement distribution. This study demonstrates the feasibility of using image-based, tooth-specific digital twins for biomechanical modelling in dentistry. The developed framework lays the groundwork for future investigations into the optimisation of restoration design and material selection in clinical applications.

Indexed as

computational modellingdental inlaydental onlayfinite element analysismicro-CT

Identifiers

PMID40710481
PMCPMC12295181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.