Evidence map›Paper›PMID 40710466›Full record

ArticleJournal of functional biomaterials2025

Biocompatibility of Hydraulic Calcium Silicate-Based Cement MTA Flow

Paulius Tušas, Josette Camilleri, Milda Alksnė, Egidijus Šimoliūnas, Saulius Drukteinis, Eglė Marija Urbonė, Virginija Bukelskienė, Vygandas Rutkūnas, Vytautė Pečiulienė

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Biological and Mechanical Comparison of Eggshell-Derived Hydroxyapatite, Calcium Hydroxide, and Mineral Trioxide Aggregate.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paulius TušasInstitute of Dentistry, Faculty of Medicine, Vilnius University, Zalgirio 115, LT-08217 Vilnius, Lithuania.
Josette CamilleriSchool of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, 5 Mill Pool Way, Birmingham B5 7EG, UK.ORCID 0000-0003-3556-6365
Milda AlksnėDepartment of Biological Models, Life Science Center, Institute of Biochemistry, Vilnius University, Sauletekio al. 7, LT-10257 Vilnius, Lithuania.
Egidijus ŠimoliūnasDepartment of Biological Models, Life Science Center, Institute of Biochemistry, Vilnius University, Sauletekio al. 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0001-5440-3591
Saulius DrukteinisInstitute of Dentistry, Faculty of Medicine, Vilnius University, Zalgirio 115, LT-08217 Vilnius, Lithuania.ORCID 0000-0001-9167-2934
Eglė Marija UrbonėInstitute of Dentistry, Faculty of Medicine, Vilnius University, Zalgirio 115, LT-08217 Vilnius, Lithuania.
Virginija BukelskienėDepartment of Biological Models, Life Science Center, Institute of Biochemistry, Vilnius University, Sauletekio al. 7, LT-10257 Vilnius, Lithuania.
Vygandas RutkūnasInstitute of Dentistry, Faculty of Medicine, Vilnius University, Zalgirio 115, LT-08217 Vilnius, Lithuania.
Vytautė PečiulienėInstitute of Dentistry, Faculty of Medicine, Vilnius University, Zalgirio 115, LT-08217 Vilnius, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimhydraulic calcium silicate-based cements (HCSCs) are widely used in endodontics for vital pulp therapy and other clinical procedures due to their favorable physicochemical and biological properties. This study evaluates the biological properties of two HCSCs-MTA Flow™ and MTA Flow™ White (in a 3:2 liquid-to-powder ratio, thick consistency)-on human dental pulp stem cells (hDPSCs). METHODOLOGY: hDPSCs were exposed to leachates from MTA Flow™, MTA Flow™ White, and ProRoot

resultsMTA Flow™ White and ProRoot

conclusionsMTA Flow™ and MTA Flow™ White, used in 3:2 thick consistency, demonstrated biocompatibility comparable to ProRoot

Indexed as

apoptosis assaybiocompatibilitycell proliferationhuman dental pulp stem cellshydraulic calcium silicate-based cement

Identifiers

PMID40710466
PMCPMC12294829

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.