Evidence map›Paper›PMID 40710458›Full record

ReviewJournal of functional biomaterials2025

Usage of Silver Nanoparticles in Orthodontic Bonding Reagents.

Janet Jisoo Lee, Meigan Niu, Zinah Shakir, Geelsu Hwang, Chun-Hsi Chung, Mark S Wolff, Zhong Zheng, Chenshuang Li

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Usage of Silver Nanoparticles in Orthodontic Appliances.Materials (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Janet Jisoo LeeSchool of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Meigan NiuSchool of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Zinah ShakirSchool of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Geelsu HwangDepartment of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-7277-5639
Chun-Hsi ChungDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mark S WolffDivision of Restorative Dentistry, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-2314-0519
Zhong ZhengDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-4905-3563
Chenshuang LiDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-6331-6983

Funding

American Academy of Periodontology Foundation Dr. Colin Richman And Family Perio.-Ortho. Interface AwardAmerican Association for Dental, Oral, and Craniofacial Research Anne D. Haffajee FellowshipAmerican Association of Orthodontists Foundation Biomedical Research AwardInternational Orthodontic Foundation Young Research Grantthe Department of Orthodontics, University of Pennsylvania School of Dental Medicine the J. Henry O'Hern Jr. Pilot Grant
6 · The paper itself

Abstract

Fixed orthodontic appliances, which are cemented to tooth surfaces, complicate the maintenance of oral hygiene and create a rough surface that is favorable for bacteria attachment. Additionally, the presence of orthodontic appliances may conceive a unique environment that interacts with cariogenic microorganisms, fostering a distinct microbial ecosystem compared to that of the patients without orthodontic appliances, thus increasing the vulnerability of tooth surfaces to demineralization and caries formation. Silver (Ag) has shown strong antimicrobial effects and has been extensively investigated in the medical field. Here, we aim to review the antibacterial properties and potential side effects of silver nanoparticles (AgNPs) when incorporated into orthodontic bonding reagents. This valuation could contribute to the development of novel bonding reagents designed to prevent the formation of white spot lesions and caries during orthodontic treatments.

Indexed as

compositeglass ionomernanoparticleorthodonticssliver

Identifiers

PMID40710458
PMCPMC12295521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.