Evidence map›Paper›PMID 40710356›Full record

ArticleCells2025

IP3R2-Mediated Astrocytic Ca

Mario Fernández de la Puebla, Xiaoyi Zhang, Erlend A Nagelhus, Magnar Bjørås, Wannan Tang

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mario Fernández de la PueblaDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.
Xiaoyi ZhangDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, 0372 Oslo, Norway.
Erlend A NagelhusDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, 0372 Oslo, Norway.
Magnar BjøråsDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.ORCID 0000-0001-8759-1170
Wannan TangDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.ORCID 0000-0002-2263-6435

Funding

Central Norway Regional Health Authority 28293Felles forskningsutvalg (FFU) 34226The Research Council of Norway 262552
6 · The paper itself

Abstract

Accumulating studies have shown that astrocytes are essential for regulating neurons at both synaptic and circuit levels. The main mechanism of brain astrocytic intracellular Ca

Indexed as

AstrocytesCalciumInositol 1,4,5-Trisphosphate ReceptorsLocomotionNeuronsSomatosensory CortexAnimalsCalcium SignalingMaleMiceMice, Inbred C57BLMice, KnockoutCalciumInositol 1,4,5-Trisphosphate ReceptorsIp3r2 protein, mouseastrocytesCa2+ signalinggenetically encoded calcium indicatorIP3R2locomotionneuro–glial interactionneuromodulationtwo-photon imaging

Identifiers

PMID40710356
PMCPMC12293227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.