Evidence map›Paper›PMID 40710352›Full record

ArticleCells2025

Spent Hop (

Miłosz Caban, Katarzyna Owczarek, Justyna Rosicka-Kaczmarek, Karolina Miśkiewicz, Joanna Oracz, Wojciech Pawłowski, Karolina Niewinna, Urszula Lewandowska

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miłosz CabanDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.ORCID 0000-0002-3894-3990
Katarzyna OwczarekDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.ORCID 0000-0002-1351-2406
Justyna Rosicka-KaczmarekInstitute of Food Technology and Analysis, Faculty of Biotechnology and Food Science, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.
Karolina MiśkiewiczInstitute of Food Technology and Analysis, Faculty of Biotechnology and Food Science, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.ORCID 0000-0003-2701-0754
Joanna OraczInstitute of Food Technology and Analysis, Faculty of Biotechnology and Food Science, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.ORCID 0000-0003-2469-3369
Wojciech PawłowskiDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.
Karolina NiewinnaDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.
Urszula LewandowskaDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.ORCID 0000-0002-5995-6168

Funding

Medical University of Lodz 503/1-156-04/503-11-001 and No. 503/1-156-04/503-99-010
6 · The paper itself

Abstract

The treatment of inflammatory bowel diseases (IBDs), particularly ulcerative colitis and Crohn's disease, remains a challenge. As the available therapeutic options have limited efficacy and various side effect, there is a need to identify new inflammatory modulators that can influence IBD. Natural polyphenols and polyphenol-rich extracts have been found to have preventive and therapeutic potential, including various anti-inflammatory effects. In this study, the inhibition of the formation of mediators associated with intestinal inflammation, remodelling, and angiogenesis by the spent hop extract (SHE), a polyphenol-rich extract from

Indexed as

Extracellular Signal-Regulated MAP KinasesFlaxHumulusInflammatory Bowel DiseasesNF-kappa BPlant ExtractsPolysaccharidesProto-Oncogene Proteins c-aktCell LineCytokinesHumansSignal TransductionTumor Necrosis Factor-alphaCytokinesExtracellular Signal-Regulated MAP KinasesNF-kappa BPlant ExtractsPolysaccharidesProto-Oncogene Proteins c-aktTumor Necrosis Factor-alphabioavailabilitycolonencapsulationflaxseed polysaccharidesinflammatory bowel diseasesinflammatory responseintestinepolyphenolsspent hop extract

Identifiers

PMID40710352
PMCPMC12293961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.