Evidence map›Paper›PMID 40710335›Full record

ArticleCells2025

Sigma1 Receptor Modulates Plasma Membrane and Mitochondrial Peroxiporins.

Giorgia Pellavio, Giorgia Senise, Chiara Pia Vicenzo, Umberto Laforenza

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giorgia PellavioDepartment of Molecular Medicine, Human Physiology Unit, University of Pavia, 27100 Pavia, Italy.
Giorgia SeniseDepartment of Molecular Medicine, Human Physiology Unit, University of Pavia, 27100 Pavia, Italy.
Chiara Pia VicenzoDepartment of Molecular Medicine, Human Physiology Unit, University of Pavia, 27100 Pavia, Italy.
Umberto LaforenzaDepartment of Molecular Medicine, Human Physiology Unit, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-2951-5983

Funding

Department of Molecular Medicine of the University of Pavia Dipartimenti di Eccellenza (2018-2022).
6 · The paper itself

Abstract

Sigma1 receptor (S1R) and some aquaporins (AQPs) are involved in controlling oxidative stress, but only recently has their possible interaction emerged. S1R acts by interacting with proteins in the plasma membrane and organelles and AQPs by favoring the hydrogen peroxide (H

Indexed as

AquaporinsCell MembraneMitochondriaReceptors, sigmaAnimalsHumansHydrogen PeroxideMitochondrial MembranesOxidative StressSigma-1 ReceptorAquaporinsHydrogen PeroxideReceptors, sigmaSigma-1 ReceptoraquaporinsHeLahydrogen peroxideHyPer7 biosensormitochondrial permeabilityoxidative stress

Identifiers

PMID40710335
PMCPMC12293570

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.