Evidence map›Paper›PMID 40710324›Full record

ArticleCells2025

The Expression of

Matteo Bozzo, Emanuele Serafini, Giacomo Rosa, Virginia Bazzurro, Andrea Amaroli, Sara Ferrando, Michael Schubert, Simona Candiani

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo BozzoDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.ORCID 0000-0002-7452-3758
Emanuele SerafiniDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.ORCID 0009-0008-6009-4199
Giacomo RosaDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.ORCID 0000-0002-3386-0459
Virginia BazzurroDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.
Andrea AmaroliDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.ORCID 0000-0002-0494-7942
Sara FerrandoDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.ORCID 0000-0002-5781-9709
Michael SchubertLaboratoire de Biologie du Développement de Villefranche-sur-Mer (LBDV), Institut de la Mer de Villefranche, Centre National de la Recherche Scientifique (CNRS), Sorbonne Université, 06230 Villefranche-sur-Mer, France.ORCID 0000-0002-2341-712X
Simona CandianiDipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di Genova, 16132 Genoa, Italy.ORCID 0000-0002-4453-5475

Funding

Agence Nationale de la Recherche ANR-21-CE340006-02Centre National de la Recherche Scientifique Recurrent fundingUniversity of Genoa FRA-2024
6 · The paper itself

Abstract

Serine hydroxymethyltransferases (SHMTs) are key enzymes in one-carbon metabolism, with vertebrates possessing two paralogs, cytosolic SHMT1 and mitochondrial SHMT2, implicated in nucleotide biosynthesis and glycine metabolism. In this study, we investigate the evolutionary history of animal

Indexed as

Glycine HydroxymethyltransferaseLanceletsSynaptic TransmissionAnimalsCell ProliferationGene Expression Regulation, DevelopmentalPhylogenyGlycine Hydroxymethyltransferasedevelopmentevolutionglycine biosynthesisglycinergic neuronsone-carbon metabolismserine hydroxymethyltransferase

Identifiers

PMID40710324
PMCPMC12293503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.