Differential BACH1 Expression in Basal-like Breast Tumors of Black Women Identified via Immunohistochemistry.

N M Dowling, Galina Khramtsova, Olufunmilayo Olopade, Shabnam Samankan, Bok-Soon Lee, Jiyoung Lee

Abstract read

In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

N M DowlingDepartment of Acute & Chronic Care, School of Nursing, Ashburn, VA 20147, USA.ORCID 0000-0001-8642-7299

Galina KhramtsovaCenter for Clinical Cancer Genetics and Global Health, Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

Olufunmilayo OlopadeCenter for Clinical Cancer Genetics and Global Health, Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

Shabnam SamankanGW Medical Faculty Associates, George Washington University Hospital, Washington, DC 20037, USA.

Bok-Soon LeeDepartment of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, George Washington University, Washington, DC 20037, USA.

Jiyoung LeeDepartment of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, George Washington University, Washington, DC 20037, USA.ORCID 0000-0001-8503-4805

Funding

Understanding lactate catabolism by BACH1 in triple negative breast cancerR37CA270536 · NCI · GEORGE WASHINGTON UNIVERSITY · PI Jiyoung Lee · 2022 to 2026

$2.4M

CDMRP DOD W81XWH-17-1-0261NCI NIH HHS R37 CA270536NCI NIH HHS R37CA270536

6 · The paper itself

Abstract

BACH1 has been identified as a functional regulator of cancer metastasis and metabolic signaling in breast cancer cells. However, the clinical relevance of BACH1 expression in breast tumors remains poorly understood. Using a tissue microarray from a cohort of 130 patients, we assessed the expression of BACH1 and its known target gene, MCT1 (encoded by

Indexed as

Basic-Leucine Zipper Transcription FactorsBreast NeoplasmsAdultAgedBiomarkers, TumorBlack or African AmericanFemaleHumansImmunohistochemistryMiddle AgedMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSymportersWhiteBACH1 protein, humanBasic-Leucine Zipper Transcription FactorsBiomarkers, TumorMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSymportersBACH1basal-like subtypeBlack womenbreast cancerdisparityIHC scoreMCT1race

Identifiers

PMID40710214

DOI10.3390/curroncol32070404

PMCPMC12293708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.