Evidence map›Paper›PMID 40710079›Full record

ArticleBiosensors2025

A Microsphere-Based Sensor for Point-of-Care and Non-Invasive Acetone Detection.

Oscar Osorio Perez, Ngan Anh Nguyen, Landon Denham, Asher Hendricks, Rodrigo E Dominguez, Eun Ju Jeong, Marcio S Carvalho, Mateus Lima, Jarrett Eshima, Nanxi Yu and 4 more

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oscar Osorio PerezSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.
Ngan Anh NguyenSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.
Landon DenhamSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0002-7107-8636
Asher HendricksSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.
Rodrigo E DominguezSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0002-2252-0715
Eun Ju JeongSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.
Marcio S CarvalhoDepartment of Mechanical Engineering, Pontifícia Universidade Catolica do Rio de Janeiro, Prédio Pe. Laércio Dias de Moura-R. Marquês de São Vicente, 225-6ºandar-Gávea, Rio de Janeiro 22451-900, Brazil.ORCID 0000-0002-6867-7101
Mateus LimaDepartment of Mechanical Engineering, Pontifícia Universidade Catolica do Rio de Janeiro, Prédio Pe. Laércio Dias de Moura-R. Marquês de São Vicente, 225-6ºandar-Gávea, Rio de Janeiro 22451-900, Brazil.
Jarrett EshimaSchool of Biological and Health Systems Engineering, Arizona State University, G Wing, E. Tyler Mall, Tempe, AZ 85281, USA.ORCID 0000-0003-1111-9069
Nanxi YuCenter for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, 1001 S McAllister Ave., Tempe, AZ 85281, USA.ORCID 0000-0002-8898-4467
Barbara SmithSchool of Biological and Health Systems Engineering, Arizona State University, G Wing, E. Tyler Mall, Tempe, AZ 85281, USA.ORCID 0000-0003-1758-624X
Shaopeng WangCenter for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, 1001 S McAllister Ave., Tempe, AZ 85281, USA.ORCID 0000-0002-2680-0503
Doina KulickMayo Clinic Arizona, 13208 E. Shea Blvd., Scottsdale, AZ 85259, USA.
Erica ForzaniSchool of Engineering for Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA.

Funding

Wearable sensor for passive detection and efficient treatment of multiple disordersR03EB027336 · NIBIB · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI FORZANI, ERICA SILVIA · 2019 to 2021
$145k
NIBIB NIH HHS R03 EB027336
6 · The paper itself

Abstract

Ketones, which are key biomarkers of fat oxidation, are relevant for metabolic health maintenance and disease development, making continuous monitoring essential. In this study, we introduce a novel colorimetric sensor designed for potential continuous acetone detection in biological fluids. The sensor features a polydimethylsiloxane (PDMS) shell that encapsulates a sensitive and specific liquid-core acetone-sensing probe. The microsphere sensors were characterized by evaluating their size, PDMS shell thickness, colorimetric response, and sensitivity under realistic conditions, including 100% relative humidity (RH) and CO

Indexed as

AcetoneBiosensing TechniquesMicrospheresPoint-of-Care SystemsBreath TestsColorimetryGas Chromatography-Mass SpectrometryHumansAcetoneacetone sensorbreath and skin acetonecolorimetric detectionketosisliquid-core microspheresmetabolic healthnon-invasive monitoringobesitypoint-of-care diagnosticstype 1 diabetes

Identifiers

PMID40710079
PMCPMC12293801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.