Evidence map›Paper›PMID 40710025›Full record

ArticleClinics and practice2025

Incidence of Gallstones in Patients with Obesity After Bariatric Surgery in Northern Saudi Arabia: A Cross-Sectional Study.

Abdulrahman Omar A Alali, Abdualaziz Fayez Alhumidi Alanazi, Mohammed Abdulaziz M Albarghash, Rakan Nasser Abdullah Alruweli, Mohammed Bader H Alanazi, Ibrahim Farhan B Alanazi, Turkey Saleh H Alrowaily, Rakan Khalid Marzouq Alanazi, Baraah AbuAlsel, Fadih Nada M Alenezi and 2 more

Abstract read
In one paragraph

Article in Clinics and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abdulrahman Omar A AlaliFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.ORCID 0009-0004-5118-9146
Abdualaziz Fayez Alhumidi AlanaziFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.ORCID 0009-0003-9583-1500
Mohammed Abdulaziz M AlbarghashFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Rakan Nasser Abdullah AlruweliFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.ORCID 0009-0005-4623-4472
Mohammed Bader H AlanaziFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Ibrahim Farhan B AlanaziFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Turkey Saleh H AlrowailyFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Rakan Khalid Marzouq AlanaziFaculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Baraah AbuAlselDepartment of Pathology, Faculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Fadih Nada M AleneziBariatric Surgery Center, Prince Abdulaziz Bin Musaad Hospital, Arar 73212, Saudi Arabia.ORCID 0009-0004-6507-2264
Rashad Qasem Ali OthmanDepartment of Pathology, Faculty of Medicine, Northern Border University, Arar 91431, Saudi Arabia.
Manal S FawzyCenter for Health Research, Northern Border University, Arar 73213, Saudi Arabia.ORCID 0000-0003-1252-8403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesGallstone formation (cholelithiasis) is a common and important consequence following bariatric surgery, though regional data from the Northern Border Region are limited. This study aimed to investigate the incidence and risk factors of gallstones in this population, with the goal of optimizing postoperative treatment and reducing morbidity.

methodsWe conducted a cross-sectional study using a non-probability convenience sampling technique to recruit 509 participants with varying degrees of obesity. Four hundred and ten study participants underwent bariatric surgery, of whom 73 were excluded for preoperative cholelithiasis and/or cholecystectomy. Data were collected through a self-administered, pre-validated questionnaire distributed via various social media platforms. These data included demographics, type/timing of surgery, pre/postoperative BMI, medical history, use of gallstone prophylaxis, and gallstone outcomes. Logistic regression analysis was used to identify independent predictors of gallstone formation.

resultsPostoperative cholelithiasis developed in 60.8% of patients, most commonly within the first postoperative year, with risk peaking between 7 and 12 months after surgery. Rapid and substantial postoperative weight loss, as reflected in a lower current BMI and a transition to normal or overweight status within one year, was significantly associated with an increased incidence of gallstones. Female sex (OR: 2.62, 95% CI: 1.38-4.98,

conclusionsGallstone formation after bariatric surgery in this population is influenced by female sex, rapid postoperative weight loss, and lack of prophylactic medication, while the type of surgical procedure does not significantly affect risk. Focused monitoring and preventive strategies, particularly in high-risk groups, are recommended to reduce gallstone-related complications following bariatric surgery.

Indexed as

bariatric surgerycholelithiasisgallstonesincidenceNorthern Border Regionobesityrisk factors

Identifiers

PMID40710025
PMCPMC12293454

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.