Evidence map›Paper›PMID 40710017›Full record

ReviewDiseases (Basel, Switzerland)2025

Therapeutic Implications of Menin Inhibitors in the Treatment of Acute Leukemia: A Critical Review.

Martina Canichella, Cristina Papayannidis, Carla Mazzone, Paolo de Fabritiis

Abstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martina CanichellaHematology, St. Eugenio Hospital, ASL Roma2, 00144 Rome, Italy.ORCID 0009-0006-4703-6280
Cristina PapayannidisIRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia L. e A. Seràgnoli, 40138 Bologna, Italy.
Carla MazzoneHematology, St. Eugenio Hospital, ASL Roma2, 00144 Rome, Italy.
Paolo de FabritiisHematology, St. Eugenio Hospital, ASL Roma2, 00144 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Menin inhibitors are a class of targeted agents that exemplify how a deeper understanding of leukemia pathogenesis can unify seemingly distinct genetic acute leukemia subgroups under a common therapeutic strategy. In particular, acute leukemia with

Indexed as

acute lymphoblastic leukemiaacute myeloid leukemia (AML)allogeneic hematopoietic stem cell transplantation (allo-HSCT)bleximenibenzomenibKMT2A rearrangement (KMT2Ar)NPM1 mutation (NPM1m)revumenibziftomenib

Identifiers

PMID40710017
PMCPMC12294120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.