Evidence map›Paper›PMID 40710001›Full record

ArticleDiseases (Basel, Switzerland)2025

Impact of Race on Admission, Clinical Outcomes, and Disposition in Cholangiocarcinoma: Insights from the National Inpatient Database.

Tijin A Mathew, Teresa M Varghese, Nithya Krishnakumaran, George M Varghese, Khwaja S Haq, Akshita Khosla, Rojymon Jacob, Gina Vaccaro

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tijin A MathewDepartment of Internal Medicine, Southeast Health Dothan, Dothan, AL 36301, USA.
Teresa M VargheseDepartment of Internal Medicine, Wellstar Spalding, Griffin, GA 30224, USA.
Nithya KrishnakumaranDepartment of Internal Medicine, Southeast Health Dothan, Dothan, AL 36301, USA.
George M VargheseDepartment of Cardiovascular Medicine, Stanford University, Stanford, CA 94305, USA.
Khwaja S HaqDepartment of Internal Medicine, Wellstar Spalding, Griffin, GA 30224, USA.
Akshita KhoslaDepartment of Hematology and Oncology, Louisiana State University, New Orleans, LA 70112, USA.
Rojymon JacobDepartment of Radiation Oncology, The University of Mississippi Medical Center, Jackson, MS 39216, USA.
Gina VaccaroDepartment of Hematology Oncology, Tennessee Oncology, Nashville, TN 37203, USA.ORCID 0000-0003-3934-0806

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCholangiocarcinoma, malignancies arising from the intrahepatic and extrahepatic bile ducts, has increased in incidence in the United States over the past few decades. The reported incidence of cholangiocarcinomas is high, particularly in specific racial groups such as Asian and Pacific Islander patients. Race also significantly impacts disparities in healthcare utilization and clinical outcomes. Our study focused on the impact of race on admission, clinical outcomes, and disposition of cholangiocarcinoma.

methodsWe performed a retrospective analysis of cholangiocarcinoma-related hospital admissions, using the National Inpatient Sample for the year 2022. Patients were stratified according to race into the following groups: White, African American, Hispanic, Asian or Pacific Islander, Native American, and Other. The data analysis was performed using STATA/BE version 18.5. Univariable and multivariable logistic regression models were applied to evaluate the relationship between race and clinical and healthcare utilization outcomes.

resultsIn 2022, 7479 hospitalizations were recorded for cholangiocarcinoma in the United States. Among these, 65.99% were White, 13.27% Hispanic, and 10.13% African American. There was a statistically significant difference in gender distribution across racial groups (

conclusionsThe study underscores the racial disparities among cholangiocarcinoma hospitalizations, with African American, Native American, and Asian patients facing disproportionately higher mortality and poorer in-hospital outcomes compared to White patients. This analysis highlights the healthcare strategies and policy reforms to promote equitable treatment by mitigating these disparities and to improve cholangiocarcinoma outcomes.

Indexed as

cholangiocarcinomain-hospital complicationsmortalityracial disparities

Identifiers

PMID40710001
PMCPMC12294044

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