Evidence map›Paper›PMID 40709979›Full record

ArticleDiseases (Basel, Switzerland)2025

Effects of a Food Supplement Containing Hydrolyzed Collagen on Pain Perception, Joint Range, and Quality of Life in People with Chronic Knee Pain.

Juan Carlos Salinas-Camargo, Cristian Marín-Pagán, Rosario Victoria Álvarez-Gil, Francisco Javier Martínez-Noguera, María Cabrera-Cabrera, Josep Manuel Llabrés-Laguarda, María Isabel Vasallo-Morillas, Pedro E Alcaraz

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan Carlos Salinas-CamargoResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.ORCID 0009-0007-6002-3342
Cristian Marín-PagánResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.ORCID 0000-0003-2979-8012
Rosario Victoria Álvarez-GilResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.
Francisco Javier Martínez-NogueraResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.ORCID 0000-0002-2851-9029
María Cabrera-CabreraPlantas Medicinales y Complementos Alimenticios, S.A. (PLAMECA), Av. Prat de la Riba, S/N, 08780 Pallejà, Spain.ORCID 0009-0005-8645-6635
Josep Manuel Llabrés-LaguardaPlantas Medicinales y Complementos Alimenticios, S.A. (PLAMECA), Av. Prat de la Riba, S/N, 08780 Pallejà, Spain.ORCID 0000-0002-8103-3861
María Isabel Vasallo-MorillasSan Antonio Technologies S.L., Avda. de los Jerónimos 135, 30107 Murcia, Spain.
Pedro E AlcarazResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.ORCID 0000-0002-9792-6656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundJoint pain can impair joint function and limit a person's ability to perform basic tasks and quality of life. The most used treatment is the pharmacological one. An alternative is the use of collagen-based food supplements. However, it remains a challenge to continue to develop new formulations to improve their efficacy.

objectivesThe aim was to evaluate the long-term effectiveness of a food supplement based on hydrolyzed collagen alongside other active ingredients on knee joint pain, range of motion, and quality of life questionnaires in a moderately active population.

methodsA randomized, double-blind, and controlled study with two arms was completed with 80 participants, who took the prescribed supplementation (Curarti

resultsThe supplement group showed a reduction of pain felt just after waking up in the morning. A statistically significant reduction in felt pain 3 h after exercise was observed at week 6 for the new product formula group compared to the placebo group. The symptoms associated with knee problems (KOOS) showed significant differences between groups. In functional capacity (WOMAC), it was found that the improvement was greater in the group treated with investigational formula (IF) than in the placebo group. The 36-item short form health survey (SF-36) about quality of life showed that the individuals who took IF improved with respect to those who took a placebo.

conclusionsThe intake of Curarti

Indexed as

arthritisjoint painquality of liferange of motionsupplements

Identifiers

PMID40709979
PMCPMC12293524

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.