Evidence map›Paper›PMID 40709804›Full record

ArticleSubstance use & addiction journal2026

Cannabis and Derived Cannabis Use, Motives, and Consequences Among US Young Adults: Findings From a Cross-Sectional Mediation Study.

Cassidy R LoParco, Yuxian Cui, Matthew E Rossheim, Rishika Chakraborty, Morgan Speer, Julia Chen-Sankey, Patricia A Cavazos-Rehg, Carla J Berg

Abstract read
In one paragraph

Article in Substance use & addiction journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cassidy R LoParcoDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.ORCID 0000-0003-4206-4179
Yuxian CuiDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.ORCID 0000-0003-4177-2050
Matthew E RossheimDepartment of Health Administration and Health Policy, College of Public Health, University of North Texas Health Science Center, Fort Worth, TX, USA.
Rishika ChakrabortyDepartment of Health Policy and Media Engagement, School of Nursing, George Washington University, Washington, DC, USA.
Morgan SpeerDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Julia Chen-SankeySchool of Public Health, Rutgers University, Piscataway, NJ, USA.
Patricia A Cavazos-RehgDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Carla J BergDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.

Funding

Recreational Marijuana Marketing and Young Adult Consumer Behavior - Administrative SupplementR01DA054751 · NIDA · GEORGE WASHINGTON UNIVERSITY · PI Carla J Berg, Patricia A Cavazos-Rehg · 2022 to 2026
$4.3M
Socio-structural determinants of cannabis and derived psychoactive cannabis product use and consequences among young adultsF32DA060612 · NIDA · GEORGE WASHINGTON UNIVERSITY · PI LOPARCO, CASSIDY R · 2024 to 2025
$101k
NIDA NIH HHS F32 DA060612NIDA NIH HHS R01 DA054751
6 · The paper itself

Abstract

backgroundSince the 2018 Agricultural Improvement Act, derived intoxicating cannabis products (DICPs) emerged as largely unregulated products; meanwhile, traditional cannabis use has increased. To inform effective prevention, research is needed to assess differences in motives for using cannabis

methodsWe analyzed survey data (June-November 2023) from 4031 US young adults aged 18 to 34 (average age = 26.9; 63.9% white; 59.0% female; aiming for ~50% past-month cannabis use). The analytic sample included participants reporting past-month cannabis use (n = 1968). Two cross-sectional mediation models were conducted to examine: (1) cannabis use motives (social/cognitive enhancement and coping) in relation to use-related consequences (psychophysiological and sociobehavioral) via use category (cannabis-only vs cannabis-DICP co-use) and (2) consequences in relation to use category via use motives.

resultsOverall, 54.4% reported cannabis-only use and 45.6% reported cannabis-DICP co-use. Greater enhancement and coping motives were associated with cannabis-DICP co-use (vs cannabis-only use). Regarding Model No. 1, lower cannabis coping motives and cannabis-DICP use (vs cannabis-only use) were associated with greater psychophysiological and sociobehavioral consequences, and the associations between coping and enhancement motives and psychophysiological and sociobehavioral consequences were indirectly mediated via cannabis-DICP co-use. For Model No. 2, lower psychophysiological and greater sociobehavioral consequences were associated with greater coping and enhancement motives, greater sociobehavioral consequences was associated with higher odds of cannabis-DICP co-use (vs cannabis-only use), and psychophysiological and sociobehavioral consequences were indirectly associated with cannabis-DICP co-use through enhancement and coping motives.

conclusionsConsidering the risks associated with cannabis and DICP use, future intervention and prevention efforts should focus on the observed associations to reduce risk.

Indexed as

Marijuana UseMotivationAdaptation, PsychologicalAdolescentAdultCannabisCross-Sectional StudiesFemaleHumansMaleUnited StatesYoung Adultdelta-8 tetrahydrocannabinol (THC)marijuanapsychoactivepublic healthsubstance use motives

Identifiers

PMID40709804
PMCPMC12580834

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.