ArticleJournal of cosmetic dermatology2025
Real World Case Series: Integrated Skincare With Advanced RGN-6 Serum.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
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Abstract
backgroundSkin aging is a multifactorial process with intrinsic and extrinsic factors that lead to visible signs of aging, including loss of skin elasticity, volume, dyspigmentation, wrinkles, fine lines, and dry and uneven skin. The advanced RGN-6 serum is a patent-pending, multi-ingredient serum that has been developed to address 6 dimensions of skin regeneration and combat visible signs of aging. The six dimensions of skin regeneration include: (1) barrier re-epithelialization, (2) redness and inflammation, (3) cellular energy stimulation, (4) elastin and collagen stimulation, (5) antioxidants, and (6) postinflammatory hyperpigmentation (PIH). To address these factors, the RGN-6 serum contains six active ingredients: 1% eperuline, 0.2% ectoin, 10% glycorepair, 0.2% bioceramide 603, 3% acetyl tetrapeptide-9, and 2% niacinamide. This multi-ingredient serum works to simultaneously target the most common signs of aging.
aimTo provide detailed evidence for multiple integrated skincare regimens using the advanced RGN-6 serum in facial rejuvenation.
methodsIn this real-world case series, 6 expert dermatologists with extensive experience in cosmetic and anti-aging medicine shared and discussed patient cases of advanced RGN-6 serum used in combination with energy-based facial rejuvenation procedures in a subset of women with skin of color with Fitzpatrick skin types ranging from type 3 to type 6.
resultsAfter the panel discussion, six patient cases were selected to best demonstrate the use of RGN-6 serum postprocedure.
conclusionThe panel experts agreed that twice daily application of the RGN-6 serum led to improved signs of redness, fine lines, and skin tone and evenness in all postprocedure patients.
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