ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Relationship between cellular aging, perceived stress, and cardiometabolic disease risk in Black family caregivers of persons with dementia.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The Impact of Dementia Caregiving on the Health of the Spousal Caregiver.Medicina (Kaunas, Lithuania) · 2026Review
- Relationship between cellular aging, perceived stress, and cardiometabolic disease risk in Black family caregivers of persons with dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundInformal caregivers of individuals with Alzheimer's disease and related dementias (ADRD) face significant physical and psychological demands. Chronic caregiving is linked to mental health challenges, poor cardiovascular health, and accelerated cellular aging, reflected in telomere shortening, with Black caregivers disproportionately affected.
methodsThis secondary analysis used data from Black caregivers from a randomized control trial. Telomere length was measured by qPCR. Questionnaires assessed perceived stress, sleep, depression, anxiety, and coping strategies. Salivary cortisol, inflammatory, and cardiometabolic biomarkers were measured. Pearson correlations and linear regression analyses controlled for demographic and health factors.
resultsShorter telomeres were linked to stress, poor sleep, inflammation, and cardiometabolic markers. Perceived stress was associated with negative coping strategies, anxiety, and depressive symptoms. DISCUSSION: More research is needed to uncover mechanisms linking caregiver stress to cardiovascular health, guiding tailored interventions to reduce stress and improve cardiovascular health in Black caregivers of persons with ADRD. HIGHLIGHTS: Chronic stress in Black caregivers: Chronic caregiving stress was linked to accelerated cellular aging, inflammation, and poor cardiometabolic health. Perceived stress associations: Higher perceived stress was associated with negative coping strategies, poor sleep quality, anxiety, depression, and reduced telomere length. Telomere length and cardiometabolic risk: Shorter telomere length was significantly associated with elevated cardiometabolic risk markers, including insulin resistance and increased blood pressure. Need for interventions: Findings emphasize the importance of culturally tailored interventions aimed at reducing stress and mitigating health risks in Black caregivers of persons living with Alzheimer's disease.
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