Evidence map›Paper›PMID 40709475›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

National representative seroprevalence of viral hepatitis B, C, and D seromarkers in Ukraine, 2021.

Ludmila Kasatkina, Vladyslav Fedorchenko, Iryna Sidorova, Lidia Gomenyuk, Oleksandra Yakovets, Michael Brandl, Iryna Ivanchuk, Sandra Dudareva, Olena Nesterova

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ludmila KasatkinaPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.
Vladyslav FedorchenkoPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.
Iryna SidorovaMedical Laboratory 'DILA', Kyiv, Ukraine.
Lidia GomenyukMedical Laboratory 'DILA', Kyiv, Ukraine.
Oleksandra YakovetsMedical Laboratory 'DILA', Kyiv, Ukraine.
Michael BrandlRobert Koch Institute (RKI), Berlin, Germany.
Iryna IvanchukPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.
Sandra DudarevaRobert Koch Institute (RKI), Berlin, Germany.
Olena NesterovaPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDAligned with World Health Organization (WHO) goals, Ukraine aims to eliminate viral hepatitis. While some data on viral hepatitis B and C prevalence exist among key populations, nationwide prevalence in the general population has never been assessed.AIMTo assess the prevalence of viral hepatitis B, C, and D seromarkers in Ukraine in 2021 to plan and monitor elimination measures.METHODSBlood samples available from a cross-sectional household-based SARS-CoV-2 serosurvey conducted in 2021 were tested for hepatitis C virus (HCV) antibodies, total antibodies against hepatitis B virus (HBV) core antigen (HBc), hepatitis B surface antigen (HBsAg) and hepatitis D virus (HDV) antibodies. We calculated crude and weighted proportions for anti-HCV, anti-HBc and HBsAg positivity. To account for differences in sex, age group and urbanisation level, we applied post-stratification weights using inverse probability weighting based on the distribution of the Ukrainian population. We calculated proportions positive for anti-HDV among HBsAg-positive cases and weighted regional estimates for HBV and HCV seromarkers.RESULTSWeighted prevalence of anti-HCV was 3.3% (95% CI: 2.8-4.0), anti-HBc 11.6% (95% CI: 10.8-12.5) and HBsAg 0.9% (95% CI: 0.7-1.2). Among HBsAg-positive individuals, 7.5% (95% СI: 3.0-17.9) were anti-HDV positive. We found higher prevalence of HBV and HCV seromarkers among men and in southern Ukraine.CONCLUSIONHBsAg prevalence and considerably high anti-HBc and anti-HCV prevalence indicate substantial lifetime exposure. This reinforces the necessity of sustained prevention such as HBV vaccination of newborns and groups at increased risk, regular hepatitis B and C screening, early treatment, and raising awareness to reduce ongoing transmission.

Indexed as

COVID-19Hepatitis BHepatitis CHepatitis DAdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesFemaleHepacivirusHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B virusHepatitis C AntibodiesHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis C Antibodieshepatitis Bhepatitis B virus surface antigenhepatitis Chepatitis Dnationwide representative serosurveyseroprevalenceUkraineviral hepatitis

Identifiers

PMID40709475
PMCPMC12314477

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.