ArticleTissue barriers2026
Advanced 3D-Printed hydrogel dressings incorporating platelet-rich plasma for accelerated skin repair.
Article in Tissue barriers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Next-generation epidermal patches: Bridging 3D and multidimensional printing for biomedical and personal care innovations.Bioactive materials · 2026Review
- Platelet concentrates integrated with tissue engineering scaffolds: a promising approach for wound healing application.Journal of nanobiotechnology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The restoration of cutaneous barrier function following deep skin injury remains a critical challenge in regenerative medicine. In this study, we developed a semi-occlusive wound dressing by combining sodium alginate hydrogel with platelet-rich plasma (PRP), using 3D bioprinting technology to ensure structural precision and consistent bioactive distribution. This hybrid system was engineered to support tissue repair by enhancing re-epithelialization, stimulating angiogenesis, and promoting organized extracellular matrix remodeling. In vivo experiments using full-thickness skin wounds in mice revealed that the PRP enriched dressings accelerated wound contraction and epithelial closure, especially during the early stages of healing. Histological analyses showed increased formation of capillary-like structures, a shift toward type I collagen dominance, and reduced inflammation in PRP treated groups. These effects point to a more mature and functional regenerative process. Importantly, the combination of PRP with a bioprinted hydrogel scaffold not only facilitated structural recovery but also contributed to restoring the physiological integrity of the skin barrier. This approach offers a low-cost and adaptable platform with strong translational potential for the treatment of complex skin wounds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.