ArticleFrontiers in nutrition2025
Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Dietary and nutritional strategies for reducing disease risk associated with antibiotic-induced dysbiosis.Gut microbes · 2026Review
- The hidden cost of antibiotics: microbial dysbiosis-induced SCFA imbalance and its underlying mechanisms.Frontiers in immunology · 2026Review
- Herbal and Natural Products for Antibiotic-Associated Diarrhea: A Systematic Review of Animal Studies Focusing on Molecular Microbiome and Barrier Outcomes.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Anti-inflammatory effects of natural polysaccharides: molecular mechanisms and nanotherapeutic applications.Frontiers in immunology · 2025Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A healthy gut depends on a balance of commensal and probiotic bacteria, and prolonged and inappropriate clinical use of antibiotics can cause an imbalance in the gut flora, resulting in antibiotic-associated diarrhea (AAD). Macrofungal polysaccharides are rich in bioactivities and have attracted much attention for their good performance in anti-inflammatory, antioxidant, anti-obesity and anti-tumor properties. Therefore, we explored the role of Methods: We initially prepared the water-insoluble polysaccharides derived from Results: Our results showed that DIPY effectively ameliorated AAD in mice by modulating the intestinal flora, increasing microbial diversity, the Shannon and Ace index was significantly higher in the DIPY group than in the NR group after the DIPY intervention ( Conclusion: This study demonstrated that DIPY has intestinal prebiotic function, which provides a basis for further development of functional products for the treatment of AAD.
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