Evidence map›Paper›PMID 40709334›Full record

ArticleFrontiers in nutrition2025

Differential effects of Mediterranean vs. Western diets on coronary atherosclerosis and peripheral artery transcriptomics.

Aya Jamal Abusheikha, Corbin S C Johnson, Noah Snyder-Mackler, Kip D Zimmerman, Jacob D Negrey, Kenneth L Chiou, Brett M Frye, Timothy D Howard, Carol A Shively, Thomas C Register

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aya Jamal AbusheikhaDepartment of Pathology/Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Corbin S C JohnsonDepartment of Neurology, University of Washington, Seattle, WA, United States.
Noah Snyder-MacklerCenter for Evolution and Medicine, Arizona State University, Tempe, AZ, United States.
Kip D ZimmermanCenter for Precision Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, United States.
Jacob D NegreyDepartment of Pathology/Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Kenneth L ChiouCenter for Evolution and Medicine, Arizona State University, Tempe, AZ, United States.
Brett M FryeDepartment of Pathology/Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Timothy D HowardCenter for Precision Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, United States.
Carol A ShivelyDepartment of Pathology/Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Thomas C RegisterDepartment of Pathology/Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.

Funding

Wake Forest University School of Medicine Alzheimer's Disease Research CenterP30AG072947 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUZANNE CRAFT · 2021 to 2026
$24.3M
Social and dietary modifiers of neuroinflammation and agingR00AG075241 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kenneth Lyu Chiou · 2024 to 2026
$742k
NIA NIH HHS P30 AG072947NIA NIH HHS R00 AG075241
6 · The paper itself

Abstract

Western diets and social subordination are associated with increased risk of cardiovascular disease. In this study, we investigated the impact of Western versus Mediterranean diets and social status on atherogenesis and arterial transcriptional profiles in a 30-month randomized study in middle-aged, cynomolgus monkeys (

Indexed as

arterial transcriptomeatherosclerosiscarotid arteryiliac arteryMediterranean dietnonhuman primatessocial statusWestern diet

Identifiers

PMID40709334
PMCPMC12288352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.