Evidence map›Paper›PMID 40709205›Full record

ReviewFrontiers in cardiovascular medicine2025

The relationship between programmed cell death and vascular calcification.

Jie Zheng, Zhengjie Lin, Xiaolin Zhong, Jianghua Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jie Zheng *The First Affiliated Hospital, Institute of Endocrinology and Metabolism, Center for Clinical Research in Diabetes, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Zhengjie Lin *The First Affiliated Hospital, Institute of Endocrinology and Metabolism, Center for Clinical Research in Diabetes, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Xiaolin ZhongThe First Affiliated Hospital, Institute of Endocrinology and Metabolism, Center for Clinical Research in Diabetes, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Jianghua LiuThe First Affiliated Hospital, Institute of Endocrinology and Metabolism, Center for Clinical Research in Diabetes, Hengyang Medical School, University of South China, Hengyang, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular calcification (VC) is a pathological condition closely associated with a range of cardiovascular diseases, including atherosclerosis (AS), hypertension, vascular injury, and diabetic angiopathy. Programmed cell death, encompassing apoptosis, autophagy, pyroptosis and ferroptosis, plays a pivotal role in the progression of VC. These cellular processes are intricately regulated by multiple signaling pathways, such as the Wnt/β-catenin and NF-κB pathways, among others. A deeper understanding of the roles and underlying mechanisms of programmed cell death in VC could offer valuable insights for the development of innovative therapeutic strategies targeting cardiovascular diseases.

Indexed as

atherosclerosisdiabetic angiopathyprogrammed cell deathsignaling pathwaysvascular calcification

Identifiers

PMID40709205
PMCPMC12288093

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.