Evidence map›Paper›PMID 40709187›Full record

ReviewFrontiers in immunology2025

Zebrafish xenografts in breast cancer research.

Xingyan Rong, Han Chen, Xiyuan Guo, Xiaoke Sun, Lin Li, Yingchun Ye, Chenwen Li, Siji Nian, Chengbi Liang, Qing Yuan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xingyan Rong *Public Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.
Han Chen *School of Stomatology, Southwest Medical University, Luzhou, Sichuan, China.
Xiyuan GuoPublic Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.
Xiaoke SunInstitute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, China.
Lin LiPublic Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.
Yingchun YePublic Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.
Chenwen LiPublic Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.
Siji NianPublic Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.
Chengbi LiangComponent Department, Luzhou Central Blood Station, Luzhou, Sichuan, China.
Qing YuanPublic Center of Experimental Technology, The School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) tops the list of all malignancies diagnosed in women worldwide, with many patients diagnosed only at the metastatic stage. Current therapeutic paradigms integrating early detection modalities and multimodal treatment strategies have improved outcomes, yet persistent challenges in managing advanced/metastatic cases result in suboptimal 5-year survival rates. Therefore, it is imperative to develop novel therapeutic strategies for BC. Zebrafish breast cancer models have received great attention in this regard, and this review highlights recent advances in BC research involving these zebrafish models.

Indexed as

Breast NeoplasmsDisease Models, AnimalZebrafishAnimalsFemaleHumansNeovascularization, PathologicXenograft Model Antitumor Assaysangiogenesisbreast cancerdrug screeninginvasionmetastasiszebrafish xenograft model

Identifiers

PMID40709187
PMCPMC12287052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.