ArticleCureus2025
Rheumatic Valve Disease Presenting As Mitral Stenosis and Regurgitation.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Can transesophageal echocardiography be safely deferred? A low-cost predictive model using D-dimer to exclude left atrial thrombus in treatment-naïve rheumatic mitral stenosis.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheumatic heart disease (RHD) affects many people globally, with the majority of cases in low- and middle-income countries. The disease often leads to significant valve damage, requiring surgical intervention due to complications such as regurgitation or stenosis. Although new cases have declined in high-income countries due to improved control of rheumatic fever (RF), chronic RHD remains a concern. Limited data on RHD in the US highlights the need for improved understanding and management. This case report discusses a 49-year-old male with worsening dyspnea, productive cough, and bilateral leg swelling who was diagnosed with severe mitral stenosis and regurgitation secondary to RHD. Diagnostic imaging revealed significant valve dysfunction and thrombi in the left atrial appendage, as confirmed by both echocardiography and a transesophageal echocardiogram. Despite initial management with medications and anticoagulation, the patient was transferred to a tertiary center for potential mitral valve intervention. This case highlights the importance of early identification and multimodal imaging in managing RHD, as well as the ongoing debate regarding the efficacy of mitral valve repair versus replacement.
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Registered trials
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