Evidence map›Paper›PMID 40709150›Full record

ArticleCureus2025

Rheumatic Valve Disease Presenting As Mitral Stenosis and Regurgitation.

Nismat Javed, Rosanna Pineda, Vikram Itare, Shoaib Ashraf, Gayathri Kamalakkannan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nismat JavedInternal Medicine, BronxCare Health System, Icahn School of Medicine at Mount Sinai, New York City, USA.
Rosanna PinedaInternal Medicine, BronxCare Health System, New York City, USA.
Vikram ItareCardiology, BronxCare Health System, Mount Sinai Morningside, New York City, USA.
Shoaib AshrafCardiology, BronxCare Health System, Mount Sinai Morningside, New York City, USA.
Gayathri KamalakkannanCardiovascular Disease, BronxCare Health System, New York City, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatic heart disease (RHD) affects many people globally, with the majority of cases in low- and middle-income countries. The disease often leads to significant valve damage, requiring surgical intervention due to complications such as regurgitation or stenosis. Although new cases have declined in high-income countries due to improved control of rheumatic fever (RF), chronic RHD remains a concern. Limited data on RHD in the US highlights the need for improved understanding and management. This case report discusses a 49-year-old male with worsening dyspnea, productive cough, and bilateral leg swelling who was diagnosed with severe mitral stenosis and regurgitation secondary to RHD. Diagnostic imaging revealed significant valve dysfunction and thrombi in the left atrial appendage, as confirmed by both echocardiography and a transesophageal echocardiogram. Despite initial management with medications and anticoagulation, the patient was transferred to a tertiary center for potential mitral valve intervention. This case highlights the importance of early identification and multimodal imaging in managing RHD, as well as the ongoing debate regarding the efficacy of mitral valve repair versus replacement.

Indexed as

mitral regurgitationmitral stenosisprognosisrhdtreatment

Identifiers

PMID40709150
PMCPMC12288938

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.