Evidence map›Paper›PMID 40709133›Full record

ArticleCureus2025

Chronic Hypoxia Due to Hypopharyngeal Cancer Presenting As Generalized Weakness: A Case Report.

Ryunosuke Hashikawa, Akira Kuriyama, Takumi Terai, Keigo Honda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryunosuke HashikawaDepartment of Primary Care and Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, JPN.
Akira KuriyamaDepartment of Primary Care and Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, JPN.
Takumi TeraiDepartment of Head and Neck Oncology and Innovative Treatment, Kyoto University Graduate School of Medicine, Kyoto, JPN.
Keigo HondaDepartment of Head and Neck Oncology and Innovative Treatment, Kyoto University Graduate School of Medicine, Kyoto, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generalized weakness is a presentation well associated with various underlying medical conditions such as infection and malignancy. However, the association between generalized weakness and hypoxia has rarely been described. A female patient in her late 80s with generalized weakness was admitted to our emergency department. Inspiratory stridor and hypoxia were incidentally recognized, leading to the diagnosis of hypopharyngeal cancer (HPC) with chronic hypoxia. After oxygen supplementation, the generalized weakness completely resolved until the HPC started to occlude the airway. Her unusual presentation could indicate that she did not compensate for her deteriorating hypoxia due to progressive obstruction of her upper airway. This case highlights the importance of a thorough physical examination in diagnosing generalized weakness, empowering physicians to closely evaluate the cause of generalized weakness and recognize it as a potential presentation of chronic hypoxia.

Indexed as

airwaygeneralized weaknesshypopharyngeal cancerhypoxiastridor

Identifiers

PMID40709133
PMCPMC12286760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.