Evidence map›Paper›PMID 40709121›Full record

ArticleCureus2025

Primary Hyperparathyroidism Due to an Ectopic Parathyroid Adenoma Located in the Posterior Part of the Esophagus.

Erina Nakao, Tomohiko Kimura, Hideyuki Iwamoto, Fuminori Tatsumi, Hideaki Kaneto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erina NakaoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, JPN.
Tomohiko KimuraDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, JPN.
Hideyuki IwamotoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, JPN.
Fuminori TatsumiDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, JPN.
Hideaki KanetoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid glands typically exist in pairs on the posterior surface of the thyroid, and primary hyperparathyroidism (PHPT) is often caused by adenomas in these locations. However, ectopic parathyroid glands may occasionally develop in unusual sites. We present a case of a 71-year-old female patient who exhibited gradual increases in both serum calcium and parathyroid hormone (PTH) levels, along with the development of osteoporosis, suggesting the presence of PHPT. Routine examination, including ultrasonography, sometimes fails to identify an ectopic parathyroid adenoma. In this case, further investigation using methoxyisobutylisonitrile (MIBI) scintigraphy and contrast-enhanced CT revealed an ectopic parathyroid adenoma located in the posterior part of the esophagus. After that, left parathyroidectomy was performed. Left parathyroid weight was 610 mg, and its size was 23 × 10 × 4 mm. Pathological examination confirmed the diagnosis of ectopic parathyroid adenoma. After the surgery, serum PTH and calcium levels were normalized. This case underscores the importance of considering ectopic parathyroid adenomas when ultrasonography fails to identify the lesion and highlights the importance of MIBI scintigraphy in such cases.

Indexed as

ectopic parathyroid adenomamibi scintigraphyparathyroid adenomaprimary hyperparathyroidismpth

Identifiers

PMID40709121
PMCPMC12286769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.