Evidence map›Paper›PMID 40709112›Full record

ArticleCureus2025

Associations Between Myeloid-Derived Suppressor Cells, TIM-3+ T Cells, and Clinical Factors During the Post-transplant Neutropenia Period in Patients With Multiple Myeloma.

Egor Batorov, Tamara Tyrinova, Tatyana Aristova, Vera Denisova, Dariya Batorova, Svetlana Sizikova, Galina Ushakova, Aleksandr Ostanin, Elena Chernykh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Egor BatorovLaboratory of Cellular Immunotherapy, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Tamara TyrinovaLaboratory of Cellular and Molecular Mechanisms of Immunopathology, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Tatyana AristovaDepartment of Hematology and Bone Marrow Transplantation, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Vera DenisovaDepartment of Hematology and Bone Marrow Transplantation, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Dariya BatorovaDepartment of Hematology and Bone Marrow Transplantation, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Svetlana SizikovaDepartment of Hematology and Bone Marrow Transplantation, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Galina UshakovaDepartment of Hematology and Bone Marrow Transplantation, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Aleksandr OstaninLaboratory of Cellular Immunotherapy, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.
Elena ChernykhLaboratory of Cellular Immunotherapy, Research Institute of Fundamental and Clinical Immunology, Novosibirsk, RUS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective of our study was to assess relationships between circulating myeloid-derived suppressor cell (MDSC) populations and T cell subsets, up-regulating PD-1 and TIM-3, as well as their intended association with several post-transplant clinical factors.

methodsForty-five patients with multiple myeloma (MM) were enrolled in the study. Circulating Lin

resultsTIM-3

conclusionFollowing autologous hematopoietic stem cell transplantation (HSCT), cellular interactions and the possible impact of therapeutic interventions on the immune recovery have not been fully investigated and may be of interest as predictive biomarkers and targets for novel therapies.

Indexed as

carbapenemsgranulocyte colony-stimulating factorhematopoietic stem cell transplantationmultiple myelomamyeloid-derived suppressor cellstim-3

Identifiers

PMID40709112
PMCPMC12287756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.