ArticleCureus2025
Prevalence of Transfusion-Transmitted Infections and Its Association With Blood Groups Among Blood Donors at the Blood Bank of a Tertiary Care Center.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Safe blood transfusion remains a challenge, and transmission of infections is always a concern. The detection of infectious diseases in blood donors ensures the safety of blood transfusion. Another challenge is the differences in blood group antigens due to the ability of clinically significant antibodies to cause adverse reactions. This study aimed to evaluate the pattern of distribution and the possible correlation of transfusion-transmitted infections (TTIs) with different blood groups. This study also aimed to evaluate the frequencies of minor blood group antigens detected on screening in a few infected blood donors. Methodology This study included replacement donors who were fit to donate blood after screening. After blood donation, tests for TTIs was done using the chemiluminescence immunoassay for hepatitis B virus (HBV)/human immunodeficiency virus (HIV)/hepatitis B virus (HCV), and rapid diagnostic kits were used for malaria and syphilis. Blood grouping was performed by IMMUCOR'S NEO IRIS instrument using commercial antisera. Samples of blood donors infected with TTIs over the study period of two months were also tested for minor antigens. Statistical analysis was done using SPSS Software, version 20 (IBM Corp., Armonk, NY, USA). Results In total, 46,549 blood donors were included, of whom 3,064 (6.6%) donors were reactive for TTIs, with the most prevalent being HBV infection (n = 1,183, 2.5%). In this study, 2.4% (n = 23) of the total B-negative blood donors were HCV reactive (χ
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