ArticleCureus2025
Where There's Smoke, There's Fire: Paraneoplastic Autoimmune Limbic Encephalitis.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoimmune encephalitis can be stemmed from paraneoplastic, drug-induced, post-infectious, and idiopathic etiologies. It is often but not always associated with neuronal cell surface or intracellular antigens. Regarding encephalitis in the limbic system, the patients mostly present with impairment of cognitive functions with subacute presentation, changes in personalities, memory loss, and seizures. We present a case of a patient who presented with subtle neurological symptoms and later progressed to refractory focal epileptic activities, posing a characteristic sign of limbic encephalitis. He was later diagnosed with small cell lung cancer on further workup. This case poses a classical yet challenging diagnostic puzzle alongside education on how to disentangle patients presenting with de novo neurological signs and symptoms with unremarkable initial screening assessments and investigations in acute settings.
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