Evidence map›Paper›PMID 40709070›Full record

ArticleHealth science reports2025

The Liver Knows: Preoperative MELD Score as a Predictor of Outcome in Patients Undergoing Left Ventricular Assist Device Implantation. A Single-Center Retrospective Cohort Study.

Mohamed Elbayomi, Presheet Pathare, Raphael Groß, Friedrich Mellert, Oliver Dewald

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohamed ElbayomiDepartment of Cardiac Surgery Friedrich-Alexander-University Erlangen Bavaria Germany.
Presheet PathareDepartment of Cardiac Surgery Friedrich-Alexander-University Erlangen Bavaria Germany.ORCID https://orcid.org/0000-0001-8935-9834
Raphael GroßDepartment of Cardiac Surgery Friedrich-Alexander-University Erlangen Bavaria Germany.
Friedrich MellertDepartment of Cardiac Surgery Friedrich-Alexander-University Erlangen Bavaria Germany.
Oliver DewaldDepartment of Cardiac Surgery Friedrich-Alexander-University Erlangen Bavaria Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Right-side heart failure (RSHF) jeopardizes left ventricular assist device (LVAD) short- and long-term outcomes. The model for end-stage liver disease (MELD) score is an effective means of evaluating liver dysfunction. This study aims to investigate the predictive utility of preoperative MELD on post-LVAD implantation outcomes, specifically focusing on the incidence of RSHF. Methods: This single-center retrospective cohort study included 133 patients who received durable continuous-flow LVADs with a centrifugal pump from 2015 to 2022. The primary outcome was RSHF, defined as necessitating right ventricular (RV), temporary or durable, mechanical support. The research hypothesis was that a high preoperative MELD score is associated with a higher incidence of RSHF after LVAD implantation. Results: The overall post-LVAD RSHF incidence was 18% ( Conclusion: Preoperative MELD score may predict the incidence of postoperative RSHF in LVAD patients. Candidates with elevated MELD scores should be carefully evaluated for alternative therapeutic modalities or optimized aggressively before LVAD implantation.

Indexed as

left ventricle assist deviceliver functionrisk stratification

Identifiers

PMID40709070
PMCPMC12287377

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.