Evidence map›Paper›PMID 40709051›Full record

ArticleFrontiers in stroke2024

Identification of Specific Recommendations for Prehospital Stroke Care Associated with Shorter Door-to-CT Times - an analysis of Get with the Guidelines-Stroke registry and prehospital data.

Layne Dylla, Hannah M Higgins, Courtney D Wham, Michelle Leppert, Brandy C Ravare, Kerri A Jeppson, Heather T Bina, Andrew A Monte, Sharon N Poisson

Abstract read
In one paragraph

Article in Frontiers in stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Layne DyllaDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Hannah M HigginsDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Courtney D WhamDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Michelle LeppertDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO.
Brandy C RavareDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO.
Kerri A JeppsonDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO.
Heather T BinaDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO.
Andrew A MonteDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Sharon N PoissonDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
UCHSC: Building Interdisciplinary Research Careers in Women's HealthK12HD057022 · NICHD · UNIVERSITY OF COLORADO DENVER · PI REGENSTEINER, JUDITH G., SANTORO, NANETTE F. · 2007 to 2023
$8.5M
The Colorado Building Interdisciplinary Research Careers in Women's Health ProgramK12AR084226 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER, Nanette F. Santoro · 2023 to 2026
$2.5M
American Heart Association-American Stroke Association 19CDA34660039NCATS NIH HHS UL1 TR002535NCATS NIH HHS UM1 TR004399NIAMS NIH HHS K12 AR084226NICHD NIH HHS K12 HD057022
6 · The paper itself

Abstract

Objective: Full compliance with American Heart Association (AHA) recommendations for prehospital care of stroke patients remains low. This study aims to identify components of prehospital care associated with shorter door-to-CT times. Methods: Data from a comprehensive stroke center's Get with the Guidelines-Stroke Registry was supplemented by prehospital medical records for ischemic stroke patients between January 1, 2018, and December 31, 2020. Descriptive statistics and multivariable linear regression modeling evaluated door-to-CT times for encounters compliant with AHA recommendations. Results: There were 621 ischemic stroke patients who presented via a prehospital provider, 452 of whom presented from the scene. Without adjusting for potential confounders, shorter door-to-CT times were observed with EMS documentation of a last known well time, measurement of a blood glucose lever, prenotification of suspected stroke, or full compliance with AHA recommendations. Documentation of classic stroke signs, but not documentation of a prehospital stroke scale, was also observed to have shorter door-to-CT times compared to encounters where this did not occur. Conclusions: During prehospital care of stroke, documentation of classic symptoms, obtaining a last known well time or time of symptom onset, obtaining a blood glucose level, prenotification of the receiving hospital of suspected stroke, and full guideline-compliance are associated with shorter door-to-CT times. Further studies are needed to understand if a shift in prehospital provider education, focusing on these key components of care, could lead to earlier diagnosis and treatment of acute stroke.

Indexed as

cerebrovascular accidentEMSischemic strokeprehospital emergency carestroke

Identifiers

PMID40709051
PMCPMC12288049

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.