Evidence map›Paper›PMID 40708970›Full record

ArticleFrontiers in toxicology2025

Arsenic toxicity in the

Anurag Chaturvedi, Vijay Shankar, Bibhu Simkhada, Rachel A Lyman, Patrick Freymuth, Elisabeth Howansky, Katelynne M Collins, Trudy F C Mackay, Robert R H Anholt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Conserved Molecular Responses to Arsenite Exposure inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anurag ChaturvediCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Vijay ShankarCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Bibhu SimkhadaCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Rachel A LymanCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Patrick FreymuthCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Elisabeth HowanskyCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Katelynne M CollinsCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Trudy F C MackayCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.
Robert R H AnholtCenter for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Clemson, SC, United States.

Funding

Statistical Methods for Gene Regulatory Analysis From Single Cell Genomics DataP20GM139769 · NIGMS · CLEMSON UNIVERSITY · PI ANHOLT, ROBERT R. H, ARNO, GAVIN · 2021 to 2025
$10.8M
NIGMS NIH HHS P20 GM139769
6 · The paper itself

Abstract

Arsenic is an ubiquitous environmental toxicant with harmful physiological effects, including neurotoxicity. Modulation of arsenic-induced gene expression in the brain cannot be readily studied in human subjects. However,

Indexed as

behavioral geneticsgenetic networksneurotoxicitysexual dimorphismsingle cell RNA sequencing

Identifiers

PMID40708970
PMCPMC12287011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.