Evidence map›Paper›PMID 40708888›Full record

ArticleJournal of experimental orthopaedics2025

Isolated tibial deformity is the most prevalent varus pattern in North American patients undergoing medial opening wedge high tibial osteotomy.

Takaaki Hiranaka, Takeo Tokura, Nicola D Mackay, Ryan M Degen, Kevin R Willits, Robert B Litchfield, Alan M J Getgood

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takaaki HiranakaFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.ORCID https://orcid.org/0000-0001-8671-8256
Takeo TokuraFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.
Nicola D MackayFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.
Ryan M DegenFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.
Kevin R WillitsFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.
Robert B LitchfieldFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.
Alan M J GetgoodFowler Kennedy Sports Medicine Clinic University of Western Ontario London Ontario Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the location of deformity in varus alignment in a North American population and assess early total knee arthroplasty (TKA) conversion rates and TKA-free survival following medial opening wedge high tibial osteotomy (MOWHTO) based on the bony deformity location. Methods: A retrospective analysis was performed on patients with varus alignment who underwent MOWHTO. Deformity analysis measured the hip-knee-ankle (HKA) angle, mechanical medial proximal tibial angle (mMPTA) and mechanical lateral distal femoral angle (mLDFA) using automated software. An abnormal mMPTA was defined as <85° and an abnormal mLDFA was defined as >90°. Cases were classified into four groups based on deformity location: tibial, femoral, combined or no bony deformity. The differences in TKA conversion rates among groups were analysed using the chi-square test, while TKA-free survival was determined using Kaplan-Meier survival analysis, with between-group differences assessed using the log-rank test. Results: A total of 271 patients were included (mean age: 51.6 years; mean follow-up: 3.6 years). The mean HKA angle was 173.0° ± 3.1°. Among the 271 patients, 38% ( Conclusion: In this North American cohort, various varus deformity locations were analysed, with isolated tibial deformity being the most prevalent. Regardless of deformity location, TKA conversion rates remained low, suggesting that MOWHTO may be beneficial even in patients without isolated tibial deformity. Level of Evidence: Level III.

Indexed as

bony deformitymedial opening wedge high tibial osteotomytotal knee arthroplastyvarus alignment

Identifiers

PMID40708888
PMCPMC12287972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.