Evidence map›Paper›PMID 40708857›Full record

ArticleFrontiers in bioengineering and biotechnology2025

A rapid-release pure iodine coating on titanium implants to mitigate acute periprosthetic infections.

Yong-Quan Zhang, Jie Liang, Qing-Quan Chen, Xiao-Li Huang, Wan-Ming Wang, Jin-Shui Chen, Xiu Yang

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yong-Quan Zhang *Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Jie Liang *Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Qing-Quan Chen *Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Xiao-Li HuangInstitute of Laboratory Animal Center, Fujian Medical University, Fuzhou, China.
Wan-Ming WangFuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Jin-Shui ChenFuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Xiu YangFuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periprosthetic infections remain a significant challenge in orthopedic surgeries, primarily due to bacterial biofilm formation on implant surfaces. To address this issue, we developed a novel iodine-based coating on titanium implants designed to rapidly release iodine, thereby preventing acute infections. The efficacy and safety of this coating were assessed through both Methods: The iodine coating was applied to titanium implants using electrophoretic deposition. The coated implants were characterized using scanning electron microscopy (SEM), X-ray fluorescence spectroscopy (XRF), and energy-dispersive spectroscopy (EDS). Results: The electrophoretic deposition technique successfully produced a uniform iodine coating with high iodine content and rapid release kinetics. Conclusion: This study introduces a promising iodine-based coating for titanium implants, offering a rapid and effective solution to prevent acute periprosthetic infections while maintaining biocompatibility and supporting bone healing.

Indexed as

biofilm preventioninfectionsiodineorthopedic implantstitanium

Identifiers

PMID40708857
PMCPMC12287049

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.