Evidence map›Paper›PMID 40708777›Full record

ReviewFood science & nutrition2025

Gut-Brain Axis in Obesity: How Dietary Patterns Influence Psychological Well-Being and Metabolic Health?

Faiyaz Ahmed, Muhammad Tayyab Arshad, Sammra Maqsood, Ali Ikram, Kodjo Théodore Gnedeka

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Faiyaz AhmedDepartment of Basic Health Sciences, College of Applied Medical Sciences Qassim University Buraydah Saudi Arabia.
Muhammad Tayyab ArshadFunctional Food and Nutrition Program, Faculty of Agro-Industry Prince of Songkla University Songkhla Thailand.ORCID https://orcid.org/0009-0007-5290-7631
Sammra MaqsoodNational Institute of Food Science and Technology University of Agriculture Faisalabad Faisalabad Pakistan.ORCID https://orcid.org/0000-0001-6650-9203
Ali IkramUniversity Institute of Food Science and Technology The University of Lahore Lahore Pakistan.ORCID https://orcid.org/0000-0002-2893-4249
Kodjo Théodore GnedekaTogo Laboratory: Applied Agricultural Economics Research Team (ERE2A) University of Lomé Lome Togo.ORCID https://orcid.org/0000-0003-0063-4524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combining nutritional, microbial, and psychological factors, the gut-brain axis plays a pivotal role in obesity. In distinction to Western diets which are heavy in processed foods and disturb gut microbiota leading to inflammation and metabolic dysfunction while Mediterranean diets which are rich in fiber and probiotics improve microbial diversity and psychological health. Emotional consumption, aggravated by psychological states such as sadness and stress, is a prominent driver of the obesity epidemic. Nutritional interventions such as prebiotics and fiber are needed to restore metabolic and emotional balance since dysbiosis in the gut has been linked with insulin resistance and type 2 diabetes. Recent findings demonstrate that treatment could be optimized through tailored dietary intervention depending on microbial patterns. One potential all-encompassing strategy for the treatment of obesity is an integrative strategy that combines dietary modification with psychological counseling and pharmacologic therapies. Diet, gut and mental health are inversely correlated with each other, and this review summarizes the current evidence on the gut-brain axis in obesity. To treat the multi-factorial etiology of obesity, future research should explore drugs that act on the microbiome as well as multi-disciplinary strategies.

Indexed as

gut microbiotainsulin resistanceobesityprobiotics

Identifiers

PMID40708777
PMCPMC12288621

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.