ArticleDevelopment & reproduction2025
Effects of Nonylphenol on the Secretions of Catecholamines, Gonadotropin-Releasing Hormone (GnRH) and Kisspeptin from Short-Term Incubated Rat Hypothalamus.
Article in Development & reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Previously, we developed a short-term incubation method of rat adrenal and demonstrated that nonylphenol (NP) exposure could induce changes in secretions of adrenal hormones. In the present study, the effects of NP on changes in hormonal secretion from hypothalamus were investigated. The catecholamine levels were measured using high-performance liquid chromatography with electrochemical detection (HPLC-ECD) and the levels of gonadotropin-releasing hormone (GnRH) and kisspeptin were measured using enzyme-linked immunosorbent assay (ELISA). The norepinephrine (NE) levels from NP-treated male and female hypothalamus were not significantly changed across the entire treatment concentration (from 1 nM to 1 μM), except male 10 nM-treated group which were significantly lower than control (
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