Evidence map›Paper›PMID 40708548›Full record

ArticleInternational wound journal2025

Distribution of Carbapenemase Genes Associated With Global High-Risk Sequence Types in Pseudomonas aeruginosa Isolates From Chronic Leg Ulcer Patients in Northern Tanzania.

Lameck Pashet Sengeruan, Omar Said Omar, Livin E Kanje, Patrick Kimu, Boaz Wadugu, Marco van Zwetselaar, Happiness Kumburu, Tolbert Sonda, Samwel Chugulu, Jere Mshana

Abstract read
In one paragraph

Article in International wound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. First report of a DIM-1-producingAntimicrobial agents and chemotherapy · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lameck Pashet SengeruanKishapu District Council, Shinyanga, Tanzania.ORCID https://orcid.org/0000-0003-3854-8998
Omar Said OmarGeneral Surgery Department, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Livin E KanjeGenomics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Patrick KimuBioinformatics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Boaz WaduguGenomics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Marco van ZwetselaarBioinformatics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Happiness KumburuGenomics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Tolbert SondaBioinformatics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Samwel ChuguluGeneral Surgery Department, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Jere MshanaGeneral Surgery Department, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Funding

Seq-Africa FF25-286
6 · The paper itself

Abstract

Carbapenem-resistant Pseudomonas aeruginosa exacerbates the healing of chronic leg ulcer among patients. Further, production and dissemination of the carbapenemase genes are associated with P. aeruginosa high-risk sequence types. Hence, understanding the population structure of these organisms is essential for healthcare personnel to establish effective leg ulcers care management, prevention interventions and control strategies particularly in regions with poor diagnosis. A cross-sectional study included inpatients and outpatients with chronic leg ulcers was conducted from August 2022 to April 2023 in 2 hospitals in Kilimanjaro region. Antimicrobial susceptibility testing was done by using the disc diffusion method. Further, whole genome sequencing was performed to study the genotypic characteristics of the isolates. Ten of 92 participants were positive for genus Pseudomonas isolates upon culture during the study period. Ambler class D carbapenemase genes were carried in all 8 isolates, and class B (

Indexed as

Bacterial Proteinsbeta-LactamasesLeg UlcerPseudomonas aeruginosaPseudomonas InfectionsAdultAgedAnti-Bacterial AgentsChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedTanzaniaAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasescarbapenemasecarbapenemse genesPseudomonas aeruginosasequence types

Identifiers

PMID40708548
PMCPMC12290302

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.