Evidence map›Paper›PMID 40708315›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2025

Playing Hard with Si: Challenges and Opportunities for New Materials in Radiation Therapy Dosimetry.

James Cayley, Ilia Filipev, Jeremy A Davis, Vincent de Rover, Dean Cutajar, Enbang Li, Bradley M Oborn, Marco Petasecca, Anatoly Rosenfeld, Michael L F Lerch

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

James CayleyCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0009-0006-9037-770X
Ilia FilipevCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0002-6971-4955
Jeremy A DavisCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0001-9773-8973
Vincent de RoverCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0009-0003-8055-2373
Dean CutajarCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0002-4384-7856
Enbang LiCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0001-7655-514X
Bradley M ObornCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0002-1672-6231
Marco PetaseccaCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0001-5958-7457
Anatoly RosenfeldCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0001-5116-6308
Michael L F LerchCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, 2522, Australia.ORCID https://orcid.org/0000-0002-2406-9972

Funding

AINSE Ltd. Postgraduate Research Award (PGRA)
6 · The paper itself

Abstract

The sophistication and diversity of radiation medicine modalities continue to increase significantly in both cancer imaging and cancer radiation therapy. With over 50% of cancer patients receiving some form of radiation procedure as part of their cancer management plan, the importance and impact of quantitative radiation detector systems for quality assurance in radiation medicine should not be underestimated. There are numerous challenges faced by silicon-based detector systems used for dosimetry in radiation therapy that are discussed in this review article, especially considering emerging radiation therapy modalities that incorporate ultra-high irradiation dose-rates (e.g., MRT, FLASH-RT, VHEE-RT), while others utilize mixed radiation fields (e.g., proton-RT, heavy ion therapy) or diffusion-based dose delivery techniques (e.g., Alpha DaRT). Such challenges create exciting opportunities for new radiation detector materials. This concise review paper explores the role of silicon in radiation detection applications and highlights the challenges it faces in achieving optimal performance. Additionally, this review discusses new materials that are emerging as strong candidates for the next generation of radiation detectors, emphasizing both the opportunities and challenges associated with these materials.

Indexed as

RadiometrySiliconHumansSiliconelectronic dosimetrymedical radiation physicsradiation medicineradiation therapy materials science and engineeringsilicon dosimeterssolid state detectors

Identifiers

PMID40708315
PMCPMC12422085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.