Evidence map›Paper›PMID 40708293›Full record

SynthesisAnnals of work exposures and health2025

Mechanisms leading to occupational oral exposure: a systematic review and meta-analysis.

Marlene Dietz, Anke Kahl, Urs Schlüter

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Annals of work exposures and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marlene DietzUnit 4.I.4 Exposure Assessment, Exposure Science, Division 4 Hazardous Substances and Biological Agents, Federal Institute for Occupational Safety and Health (BAuA), Dortmund, Germany.ORCID 0009-0001-2486-6939
Anke KahlChair of Occupational Safety, School of Mechanical Engineering and Safety Engineering, University of Wuppertal, Wuppertal, Germany.
Urs SchlüterUnit 4.I.4 Exposure Assessment, Exposure Science, Division 4 Hazardous Substances and Biological Agents, Federal Institute for Occupational Safety and Health (BAuA), Dortmund, Germany.ORCID 0000-0003-2735-9307

Funding

German Federal Institute for Occupational Safety and Health
6 · The paper itself

Abstract

introductionIn addition to inhalation and dermal exposure, also oral exposure is relevant in the workplace, even though this exposure route is most often neglected. In order to improve the understanding of occupational oral exposure, a systematic identification of mechanisms leading to inadvertent ingestion in the workplace is needed, including the transfer of chemicals and the contribution of aerosols.

methodsA systematic literature search was conducted according to the PRISMA method including 5 databases and 9 institutional websites. Information from the included studies was extracted in concept matrices and further analyzed.

resultsOverall, 175 suitable publications were selected. Identified mechanisms leading to oral exposure were the transfer of chemicals, eg, from hands to mouth, and contributions from aerosols. Transfer influencing parameters were categorized as environmental, substance-specific, transfer pathway, surface, contact, or skin characteristics. DISCUSSION: Even though oral exposure was mainly investigated for children so far, similar mechanisms can lead to oral exposure in adults. Although the parameters characterizing the transfer of chemicals were identified and categorized, inconsistencies in nomenclature were identified, and correlations between parameters and transfer efficiencies often remained unclear.

conclusionsThe transfer of hazardous substances and the contribution of aerosols were identified as mechanisms of oral exposure. Transfer parameters and the interplay between particles from aerosols and oral exposure were discussed.

Indexed as

Hazardous SubstancesMouthOccupational ExposureAerosolsHumansAerosolsHazardous Substancesaerosolsinadvertent ingestionmechanismsoccupationoral exposurePRISMAtransfer parametersworkplace

Identifiers

PMID40708293
PMCPMC12463556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.