Evidence map›Paper›PMID 40708028›Full record

ArticleGeneral thoracic and cardiovascular surgery cases2025

COR-KNOT-induced aortic root injury during minimally invasive aortic valve replacement of a bicuspid aortic valve: a case report.

Takahiro Ishigaki, Kazuma Okamoto, Satoshi Asada, Genichi Sakaguchi

Abstract read
In one paragraph

Article in General thoracic and cardiovascular surgery cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Takahiro IshigakiDepartment of Cardiovascular Surgery, KKR Sapporo Medical Center, Hokkaido, Japan. t-ishigaki@kkr-smc.com.ORCID http://orcid.org/0000-0001-8869-2942
Kazuma OkamotoDepartment of Surgery 1, Division of Cardiovascular Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan.
Satoshi AsadaDepartment of Cardiovascular Surgery, Kindai University Faculty of Medicine, Osaka, Japan.
Genichi SakaguchiDepartment of Cardiovascular Surgery, Kindai University Faculty of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COR-KNOT device is widely used in minimally invasive cardiac surgery, and its efficacy in reducing operative time is well established. However, it has been associated with complications, such as valve leaflet perforation and prosthetic valve damage. CASE PRESENTATION: We report a rare case of aortic root injury caused by COR-KNOT usage. A 72-year-old man with severe aortic stenosis due to a bicuspid aortic valve and distorted aortic root anatomy underwent minimally invasive aortic valve replacement using the COR-KNOT. After aortotomy closure, vigorous bleeding from the aortic root was observed. Punctate injuries of the aortic root, corresponding to the COR-KNOT clip sites, were identified following re-aortic cross-clamping. The procedure was converted to median sternotomy, the aortic root injury was repaired with an autologous pericardial patch, and the bioprosthetic valve was re-implanted using hand-tied sutures. The patient recovered uneventfully.

conclusionsThis case highlights the importance of careful device selection and clip positioning in anatomically challenging cases to avoid life-threatening complications.

Indexed as

Aortic injuryComplicationCOR-KNOTMinimally invasive aortic valve repair

Identifiers

PMID40708028
PMCPMC12291292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.