Evidence map›Paper›PMID 40707966›Full record

ReviewJournal of biomedical science2025

Smart hydrogels for in situ tissue drug delivery.

Shih-Ho Lin, Shan-Hui Hsu

Abstract readReview
In one paragraph

Review in Journal of biomedical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  10. Nanosponge-integrated hydrogel ofFrontiers in pharmacology · 2026
    Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shih-Ho LinInstitute of Polymer Science and Engineering, National Taiwan University, No. 1, Sec. 4 Roosevelt Road, Taipei, 106319, Taiwan, ROC.ORCID http://orcid.org/0009-0008-2708-1521
Shan-Hui HsuInstitute of Polymer Science and Engineering, National Taiwan University, No. 1, Sec. 4 Roosevelt Road, Taipei, 106319, Taiwan, ROC. shhsu@ntu.edu.tw.ORCID http://orcid.org/0000-0003-3399-055X

Funding

National Health Research Institutes CS-113-PP-15National Science and Technology Council NSTC 111-2221-E-002-052-MY3
6 · The paper itself

Abstract

The application of smart hydrogels has become a booming research frontier in biomedical engineering. With the development of intelligent drug delivery systems, various biomimetic and biodegradable hydrogels are employed for localized drug delivery to tissues in the preclinical applications. These advanced materials are designed to match the diverse environmental and functional requirements of various tissue types and organs. This article discusses the attractive characteristics of smart hydrogels as delivery systems and reviews the design of a range of smart hydrogels, as well as the challenges of tissue-specific drug delivery, focusing on the last 5 years of frontward research.

Indexed as

Drug Delivery SystemsHydrogelsAnimalsHumansTissue EngineeringHydrogelsControlled releaseDrug deliveryHydrogelsSmart hydrogels

Identifiers

PMID40707966
PMCPMC12291384

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.