Evidence map›Paper›PMID 40707965›Full record

ArticleInfectious diseases of poverty2025

Clinical confirmation of an infection with Echinococcus multilocularis (Mongolian genotype): first case report of human alveolar echinococcosis in Inner Mongolia, China.

Xu Wang, Zhan-Jun Xiao, Chui-Zhao Xue, Wen-Ting Wu, Jiang-Hui Yang, Chun Yan, Ying Wang, Yan Kui, Wen-Bo Luo, Xi Du and 6 more

Abstract readCase Reports
In one paragraph

Article in Infectious diseases of poverty, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xu WangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory On Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, China.
Zhan-Jun XiaoXilingol League Central Hospital, Xilinhot, China.
Chui-Zhao XueNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory On Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, China.
Wen-Ting WuBeijing Center for Disease Control and Prevention, Beijing, China.
Jiang-Hui YangBeijing Tsinghua Changgung Hospital, Beijing, China.
Chun YanNew Barga Right Banner Center for Disease Control and Prevention, Hulun-Buir, China.
Ying WangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory On Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, China.
Yan KuiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory On Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, China.
Wen-Bo LuoInner Mongolia Autonomous Regional Center for Disease Control and Prevention, Hohhot, China.
Xi DuNew Barga Right Banner Center for Disease Control and Prevention, Hulun-Buir, China.
Run-Na ZanChifeng City Center for Disease Control and Prevention, Chifeng, China.
Rong-Jian ShangBairin Left Banner Center for Disease Control and Prevention, Chifeng, China.
Sa LiChangping District Center for Disease Control and Prevention, Beijing, China.
Rigen NaNew Barga Right Banner Center for Disease Control and Prevention, Hulun-Buir, China.
Shuai HanNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory On Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, China. hanshuai@nipd.chinacdc.cn.ORCID http://orcid.org/0009-0001-2729-9642
Shi-Zhu LiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory On Parasite and Vector Biology, Ministry of Health; World Health Organization Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, China. lisz@chinacdc.cn.

Funding

National Natural Science Foundation of China 82404325Three-Year Initiative Plan for Strengthening Public Health System Construction in Shanghai (2023-2025) Key Discipline Project GWVI-11.1-12
6 · The paper itself

Abstract

backgroundAlveolar echinococcosis (AE), caused by the larval stage of Echinococcus multilocularis, poses a substantial global health challenge due to its high mortality profile. This study reports the inaugural human infection of echinococcosis caused by the Mongolian genotype of E. multilocularis in China, also the first reported indigenous AE case in Inner Mongolia. CASE PRESENTATION: A 58-year-old female pastoralist from Inner Mongolia, who had no endemic region exposure history but prolonged occupational contact with dogs, presented with severe AE. Clinical examinations revealed a massive hepatic lesion exceeding 10 cm in diameter, accompanied by elevated eosinophils (0.90 × 10

conclusionsThis report provides the primary evidence of a locally acquired human AE infection in China caused by the Mongolian genotype of Echinococcus multilocularis. The discovery of this case challenges historical classifications of echinococcosis endemic areas. The findings call for revised AE-endemic identification criteria, improved AE diagnostic protocols, and enhanced AE surveillance in the Inner Mongolia region to generate further epidemiological evidence and information on disease progression.

Indexed as

EchinococcosisEchinococcosis, HepaticEchinococcus multilocularisAnimalsChinaDogsFatal OutcomeFemaleGenotypeHumansLiver TransplantationMiddle AgedPhylogenyAlveolar echinococcosisChinaEchinococcus multilocularisInner MongoliaMongolian genotype

Identifiers

PMID40707965
PMCPMC12288280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.