ReviewJournal of nanobiotechnology2025
A comprehensive review of unlocking the potential of lignin-derived biomaterials: from lignin structure to biomedical application.
Review in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Lignin-Based Fluorescent Polymers: From Aggregation-Induced Emission Mechanism to Intelligent Bone Regeneration.Macromolecular bioscience · 2026Review
- Covalently Immobilized Lignin-Xanthene Conjugates for Persistent Surface Photochemistry and Self-Sterilizing Interfaces Under Ambient Visible Light.Macromolecular rapid communications · 2026Article
- Protein-Carbohydrate Interactions in Food Matrices and Their Effects on Food Quality.Foods (Basel, Switzerland) · 2026Review
- Tomato-derived carbon quantum dots: composition-driven structure and copper sensing potential.Scientific reports · 2026Article
- Molecular Insights into Lignin Bioactivity: From Structural Architecture to Sustainable Food Industry Applications.International journal of molecular sciences · 2026Review
- From structural complexity to circular applications: a comparative review of the enzymatic degradation of polydopamine, tannins, lignins, and melanins.RSC advances · 2026Review
- Biomaterials' Role in Improving Patient Care from Drug Testing and Delivery to Theragnostics and Regenerative Medicine.Journal of functional biomaterials · 2026Review
- Recycled Polyurethane Glycolysate and Glycerolysate as Sustainable Plasticizers for Lignin-Filled NBR Composites.Materials (Basel, Switzerland) · 2026Article
- Article
- Nanoparticle-Based Tolerogenic Vaccines: Next-Generation Strategies for Autoimmune and Allergic Disease Therapies.Angewandte Chemie (International ed. in English) · 2026Review
- Lignin/alginate biomaterials as a promising complementary approach in ocular chlamydial infection.Frontiers in cellular and infection microbiology · 2026Article
- Nanotherapeutic Strategies for Osteoarthritis: Targeting Aging, Metabolism and Inflammation.International journal of nanomedicine · 2026Review
- Harnessing plant lignin for sustainable materials and chemicals: integrating biosynthesis, structural diversity, and circular bioeconomy perspectives.Frontiers in plant science · 2026Review
- Magnetized phyto-adsorbents for industrial dye removal: functionalization and mechanistic insights for sustainable wastewater remediation.RSC advances · 2025Review
- Article
- Synthesis of Few-Layer Graphene from Lignin and Its Application for the Creation of Thermally Conductive and UV-Protective Coatings.Materials (Basel, Switzerland) · 2025Article
- The Importance of Molecular Size, Concentration, and Thermal Conditions in Enhancing Lignin Derivatives' Interactions with Skin-like Membranes: Implications for Cosmetic and Therapeutic Applications.International journal of molecular sciences · 2025Article
- Lignin-Modified Single-Use Graphite Electrodes: Electrochemical Detection of DNA, Mitomycin C, and Their Interaction.Sensors (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Inspired by natural organisms, biomimetic materials with exceptional biocompatibility, degradability, and multifunctionality have emerged as promising candidates for biomedical applications. Lignin, a plant-derived organic polymer, has gained attention due to its intrinsic antioxidant activity, adhesive properties, and biocompatibility. Despite its structural advantages, challenges in stability, biodegradability, and practical implementation hinder its utilization. Structural modifications through chemical/physical treatments or microbial/enzymatic can optimize lignin's bioactivity, mechanical strength, and adhesion, enabling applications in drug delivery, Ultraviolet (UV) shielding, sensing, and wound healing. This review outlines lignin sources, modification principles, and adhesion of biomaterials mechanisms, while showcasing innovative lignin-based materials in biomedical contexts. We highlight their roles in therapeutic delivery systems, tissue engineering & regenerative medicine, and functional biomedical devices, emphasizing lignin's low toxicity and environmental adaptability. By addressing current limitations in processing techniques and clinical translation, we discuss lignin's potential to bridge laboratory research and practical medical solutions. The analysis concludes with an evaluation of lignin's untapped value in sustainable biomedicine, proposing strategies to overcome scalability and standardization barriers. This synthesis provides critical insights for advancing lignin-based technologies toward clinical implementation while maintaining ecological sustainability.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.