Evidence map›Paper›PMID 40707930›Full record

ArticleBMC musculoskeletal disorders2025

Prevalence of femoral nerve neurodynamic disorder in patients with patellofemoral pain syndrome: a cross-sectional study.

Soheila Zamani, Maryam Abbaszadeh-Amirdehi, Ghadamali Talebi, Mehdi Tavassoli, Seyed Mokhtar Esmaeilnejadganji, Hemmat Gholinia

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Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Soheila ZamaniDepartment of Physiotherapy, School of Rehabilitation, Babol University of Medical Sciences, Babol, Iran.
Maryam Abbaszadeh-AmirdehiMobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR, Iran. abbaszadeh_m@alumnus.tums.ac.ir.
Ghadamali TalebiMobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR, Iran.
Mehdi TavassoliDepartment of Orthopedic, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
Seyed Mokhtar EsmaeilnejadganjiDepartment of Orthopedic, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
Hemmat GholiniaHealth Research Center, Babol University of Medical Sciences, Babol, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatellofemoral pain syndrome (PFPS) is among the most prevalent causes of knee pain in young adults. Emerging evidence suggests that musculoskeletal pain syndromes, including PFPS, may be associated with neurodynamic disorders. The aim of this study was to investigate the prevalence of femoral nerve neurodynamic disorders in patients with PFPS and to examine the association between these disorders and various clinical and demographic variables, including age, sex, body mass index, pain intensity, history of low back pain, functional ability, and rectus femoris shortness.

methodsIn this cross-sectional study, one hundred patients with unilateral PFPS aged 18-44 years participated. The femoral slump test (FST) and the prone knee bending (PKB) test were employed to assess neurodynamic disorders of the femoral nerve. The associations between the results of neurodynamic tests and selected clinical and demographic variables were evaluated using logistic regression analysis.

resultsThe prevalence of femoral nerve neurodynamic disorder in PFPS patients based on FST and PKB was 25% and 36% respectively. No significant associations were observed between FST results and the demographic or clinical variables of PFPS patients. In contrast, PKB results demonstrated significant associations with functional ability (OR = 0.96; 95% CI = 0.93-0.99), rectus femoris shortness (OR = 2.9; 95% CI = 1.15-7.33), and pain intensity (OR = 2.04; 95% CI = 1.36-3.07).

conclusionMore than one-quarter of PFPS patients exhibited increased mechanosensitivity of the femoral nerve, indicating a notable prevalence of neurodynamic disorders within this population. Nevertheless, the cross-sectional design and use of convenience sampling may limit the generalizability of these findings. These findings underscore the importance of incorporating neurodynamic assessments into the clinical evaluation of PFPS patients to facilitate more effective management.

Indexed as

Femoral NerveFemoral NeuropathyPatellofemoral Pain SyndromeAdolescentAdultCross-Sectional StudiesFemaleHumansMalePain MeasurementPrevalenceYoung AdultFemoral nerveFemoral slump testKnee jointNeurodynamicPatellofemoral pain syndromeProne knee bending

Identifiers

PMID40707930
PMCPMC12288218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.