Evidence map›Paper›PMID 40707887›Full record

ArticleBMC nephrology2025

CKRT coagulation risk prediction and nursing feedback model based on intelligent algorithms.

Xianrong Xu, Mou Chen, Lvjing Chen, Kaixing Huang, Shiqi Cao, Wenwen Gao, Kang Liu, Buyun Wu, Huijuan Mao

Abstract read
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xianrong XuDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China. xuxianrong@jsph.org.cn.
Mou ChenDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Lvjing ChenDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Kaixing HuangDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Shiqi CaoDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Wenwen GaoDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Kang LiuDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Buyun WuDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.
Huijuan MaoDepartment of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, #300, Nanjing, 210029, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo construct an intelligent Continuous Kidney Replacement Therapy nursing feedback model to predict extracorporeal coagulation risk and support timely clinical decisions.

methodsAnalyzed 1,354 treatment records from 143 patients to identify new data features relevant to Continuous Kidney Replacement Therapy nursing. The data was preprocessed, and new variables were derived to serve as model inputs. A hybrid machine learning algorithm was applied to predict the timing of Continuous Kidney Replacement Therapy initiation for patients with acute kidney injury. Extensive numerical experiments were conducted to optimize model parameters and evaluate performance, ensuring high accuracy, stability, and superior AUC values for reliable predictions.

resultsUnivariate analysis identified eight factors significantly affecting coagulation risk, including treatment mode, anticoagulation method, blood pump stoppage, and insufficient blood flow (P < 0.001). Logistic regression analysis indicated that treatment mode and anticoagulation method were key factors influencing extracorporeal coagulation during Continuous Kidney Replacement Therapy, with the highest regression coefficient observed for heparin-free anticoagulation (β = 2.209). The prediction model achieved an AUC of 0.87 (P < 0.001) and an accuracy rate of 99.21%, significantly outperforming the performance of other models.

conclusionThe intelligent Continuous Kidney Replacement Therapy nursing feedback model improves prediction accuracy while reducing redundant information. This model helps mitigate the risk of missing urgent conditions in patients under limited healthcare resources and lowers the frequency of extracorporeal coagulation events during Continuous Kidney Replacement Therapy. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Acute Kidney InjuryAlgorithmsContinuous Renal Replacement TherapyAgedAnticoagulantsClassification AlgorithmsFeedbackFemaleHumansMachine LearningMaleMiddle AgedPrediction AlgorithmsPredictive Learning ModelsRisk AssessmentAnticoagulantsContinuous kidney replacement therapyExtracorporeal circulation early warningLasso regressionMachine learning algorithmNursing feedback model

Identifiers

PMID40707887
PMCPMC12291474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.